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GlossaryCaspase-9

enzyme initiating programmed cell death in response to damage

Caspase-9 is an enzyme that plays a crucial role in the process of apoptosis, which is the programmed cell death essential for maintaining healthy tissue and organ function. It is activated in response to cellular stress or damage and initiates a cascade of events leading to the orderly dismantling of the cell. This enzyme is also known as Apoptotic protease Mch-6 and is vital for preventing the accumulation of damaged or potentially cancerous cells.

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Assessment of the Effect of Ficus Carica Leaf Extract on B16F10 Melanoma Cancer Cells: The Roles of p53, Caspase-3, and Caspase-9 in Inducing Intrinsic Apoptosis Cascade

research Assessment of the Effect of Ficus Carica Leaf Extract on B16F10 Melanoma Cancer Cells: The Roles of p53, Caspase-3, and Caspase-9 in Inducing Intrinsic Apoptosis Cascade

1 citations , October 2021 in “Jundishapur Journal of Natural Pharmaceutical Products”

Ficus carica leaf extract may help treat melanoma by promoting cancer cell death without harming normal cells.

research Shen-Ying-Yang-Zhen Formula Promotes Angiogenesis Around Hair Follicles, Alleviates Oxidative Stress, and Inhibits Hair Follicle Apoptosis Through the VEGF/Akt/Caspase-9 Signaling Axis

June 2025 in “Phytomedicine”

The formula may improve hair growth and health by boosting blood flow and reducing cell stress.

research NLRP1 Promotes Tumor Growth by Enhancing Inflammasome Activation and Suppressing Caspase-3 Activity in Human Melanoma

1 citations , April 2016 in “Journal of Investigative Dermatology”

NLRP1 helps melanoma tumors grow by boosting inflammasome activation and reducing caspase-3 activity.

research Beneficial Effects of Astragaloside IV for Hair Loss via Inhibition of Fas/FasL-Mediated Apoptotic Signaling

29 citations , March 2014 in “PloS one”

Astragaloside IV may help prevent hair loss by blocking a specific pathway that leads to cell death.

research Apoptotic Cells Represent a Dynamic Stem Cell Niche Governing Proliferation and Tissue Regeneration

25 citations , June 2021 in “Developmental Cell”

Dying cells can help with faster healing and new hair growth by releasing a growth-promoting molecule.

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community Hair loss causes are still a myth.

in Chat 16 upvotes 3 years ago

The conversation discusses the complexity of hair loss causes, suggesting that DHT sensitivity alone doesn't fully explain it. Treatments mentioned include finasteride and dutasteride.

community Don't use PP405 from everychem. it is likely fake.

in Research/Science 60 upvotes 2 months ago

PP405 from Everychem is likely fake and potentially harmful, with concerns about its stability and the risk of using the wrong MPC inhibitor, which could damage hair follicles. The real PP405 was studied under strict conditions, and DIY attempts are discouraged due to unknown formulation and quality control.