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Research

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research Hair of the mouse: A skin bacteria “cocktail” gets follicles back on their feet

1 citations , May 2021 in “Cell Host & Microbe”

This study reports that skin bacteria can accelerate hair follicle regeneration and improve wound healing through IL-1β signaling, by activating keratinocytes in a pathway involving IL1R/Myd88.

research Skin bacteriota ameliorates androgenetic alopecia via harmonizing skin immuno inflammatory balance

March 2026 in “Brazilian Journal of Microbiology”

This study found that restoring the skin microbiome significantly improved hair growth and skin condition in androgenic alopecia model mice by modulating the immune-inflammatory balance, highlighting the potential of bacterial-based therapies for hair loss.

research Inhibitory effect of mozuku seaweed-derived ultra-high-molecular-weight fucoidan on the growth of indigenous skin bacteria

January 2023 in “Fundamental toxicological sciences”

In this study, mozuku-derived ultra-high-molecular-weight fucoidan was found to inhibit the growth of skin bacteria like Staphylococcus aureus but not other tested bacteria such as Cutibacterium acnes.

research 613 Bacteria induce skin regeneration via IL-1β signaling

April 2021 in “Journal of Investigative Dermatology”

This study found that skin bacteria promote regeneration in wound-induced hair follicle neogenesis, suggesting a role for IL-1β signaling and challenging the belief that infection inhibits healing.

research 795 Bacteria induce skin regeneration

June 2020 in “Journal of Investigative Dermatology”

This study found that increasing commensal bacterial load on the skin enhances wound-induced hair follicle neogenesis in mice, mediated through IL1R-MyD88 signaling pathways.

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Community Join

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community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

63 upvotes 2 years ago

Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

community Haircafe - TOPICAL minoxidil is an anti aging drug

in Minoxidil 245 upvotes 1 year ago

Topical minoxidil may cause skin aging effects like wrinkles and dark circles, possibly due to its alcohol content, while oral finasteride is reported to make users look younger. Switching to oral minoxidil or using moisturizers might help reduce these skin issues.

community Unexpected Hair Growth

5 upvotes 9 years ago

A 24-year-old male experienced unexpected hair growth and improved skin and nails after adding daily vegetable juices, including carrot, spinach, celery, and beet, to his diet. He is not using any other treatments like minoxidil, finasteride, or RU58841.

community Has anyone tried tretinoin with seb derm and had any flare-ups as a result?

4 upvotes 7 months ago

Tretinoin can irritate seborrheic dermatitis, but using it with a moisturizer on calm skin may help. Parallel Health's skin microbiome testing and phage therapy are suggested for persistent issues.

community How to take care of the microneedler?

in Microneedling 7 upvotes 1 year ago

Disinfecting microneedlers is important to prevent infection, with suggestions to use high-percentage alcohol or denture tablets for sterilization. Rollers may cause skin damage, so stamps or pens are recommended for safer microneedling.

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Learn

7 / 33 results

learn Azelaic Acid

Acid used in acne and rosacea creams

learn Biotin

B vitamin, often sold as a hair supplement

learn Thymosin Beta 4

learn Neem Oil

Oil from the neem tree, used in traditional remedies

learn Melatonin

Can melatonin cause side effects on the skin or hair? No study links melatonin to hair loss; reports are anecdotal. Some users report scalp dryness or irritation from topical products, and a safety review lists mainly mild side effects such as sleepiness and headache.

learn Follistatin

Can follistatin be applied to the skin, and does any form of it treat hair loss? No study shows that follistatin applied to the skin works, and no form of follistatin is an approved or proven hair-loss treatment. Follistatin injections, "research peptides" and gene therapies sold outside regulated trials are unapproved and of unknown safety.

learn Scalp Micropigmentation

Is scalp micropigmentation suitable for people with sensitive skin? Providers say scalp micropigmentation suits most skin types and describe patch tests, hypoallergenic pigments and a skin consultation for sensitive skin. These are provider claims rather than independent safety evidence, and pigment reactions remain a risk.

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Experts

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SMP Specialist
Noelle Skin
Nice, France

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Noelle Skin