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research Clinical Translation of Microbiome Research in Alopecia Areata: A New Perspective?

2 citations , May 2022 in “Cosmetics”

This review explores the potential roles of the gut and skin microbiome in alopecia areata, suggesting topical and systemic strategies for managing the condition, but it reports no new clinical results.

research In Patients With Acne Vulgaris, How Do Standard Acne Treatments Combined With Adjunct Microbiome-Targeted Therapies Compare to Standard Acne Treatments Alone in Affecting Clinical Outcomes?

May 2026 in “Rowan Digitals Works (Rowan University)”

This research review identified improved outcomes in acne treatment when oral probiotics or topical probiotic-derived formulations were added to standard therapies, with probiotics reducing acne severity and enhancing safety and tolerability compared to treatments such as 2.5% Benzoyl Peroxide and Doxycycline.

research Rare and Underappreciated Causes of Polycystic Ovarian Syndrome

January 2022 in “IntechOpen eBooks”

This review examines lesser-known factors contributing to polycystic ovarian syndrome and reports no new clinical results, emphasizing the need for further research into individualized treatment and prevention strategies.

research Understanding Pattern Hair Loss—Hair Biology Impacted by Genes, Androgens, Prostaglandins and Epigenetic Factors

3 citations , October 2021 in “Indian Journal of Plastic Surgery”

The authors concluded that pattern hair loss is a complex condition with limited treatment efficacy and two FDA-approved drugs, finasteride and minoxidil, to slow its progression.

research Polycystic Ovary Syndrome-Associated Acne: The Interplay of Hyperandrogenism, Insulin Resistance, and Therapeutic Strategies

November 2025 in “Cureus”

This review discusses the link between PCOS and acne, highlighting the roles of hyperandrogenism and insulin resistance, but it reports no new clinical findings.

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community If dutesteride and oral minoxidil doesn’t work that’s it right?

in Treatment 20 upvotes 2 years ago

A user is experiencing continued hair loss despite using 0.5mg dutasteride and 2.5mg minoxidil, and is seeking advice on why the treatments aren't working and how to address potential androgen receptor sensitivity. Replies suggest getting tested and considering scalp micropigmentation (SMP).

community 36M too late to start oral Fin and Min then get a FUE?

in General 98 upvotes 1 year ago

A 36-year-old man is considering starting oral finasteride and minoxidil, using ketoconazole shampoo, and possibly getting a 3000-graft FUE hair transplant. He previously had scalp micropigmentation but is now exploring medication due to fewer concerns about side effects.

community Could I use SMP to help disguise retrograde alopecia?

8 upvotes 1 week ago

The conversation discusses using scalp micropigmentation (SMP) to disguise retrograde alopecia, with the user considering oral minoxidil and having experienced side effects from finasteride. Suggestions include trying different haircuts like skin fades and considering the potential downsides of SMP.

community After Years of Treatment, I'm Shaving my Head and Giving Up

in Shaved/buzzed 118 upvotes 1 year ago

After years of using dutasteride and oral minoxidil without success, the individual decided to shave their head and stop treatment. They considered scalp micropigmentation and hair systems but ultimately accepted their hair loss.

community You almost wouldn’t know I’m pushing NW3 - The power of long hair

in Styling 245 upvotes 1 year ago

Users discuss hair loss and styling techniques to conceal thinning hair, mentioning treatments like finasteride and oral minoxidil. Some stop hair loss but not regrow hair, considering options like scalp micropigmentation or hair transplants.

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Learn

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learn microbiota modulator

learn Finasteride

Topical or oral? Choosing between pills and lotions according to your case. Topical finasteride offers localized treatment with fewer systemic side effects than oral finasteride.

learn Metformin

Is metformin used topically for hair loss, or only as an oral tablet? Approved metformin products are oral tablets only; there is no approved topical metformin for hair loss. Published human reports of topical use are a handful of uncontrolled, pharmacy-compounded case reports in scarring alopecia, and the most-cited clinical series actually used the oral drug.

learn Sulforaphane

Is sulforaphane used in oral supplements or topical hair treatments? Sulforaphane is primarily used in oral supplements, not topical hair treatments.

learn white tea

Is white tea more effective in topical hair products or as an oral supplement for hair growth? Neither topical nor oral white tea has any human clinical trial behind it for hair growth. Topical use has a more direct mechanistic rationale, but the only verifiable studies are a cell-culture EGCG experiment and a pharmacokinetic study with no hair outcomes.

learn Estradiol

How does topical Estradiol compare to oral Estradiol in treating alopecia? Topical estradiol delivers hormone to the scalp with less systemic exposure, but evidence is thin and it is still a hormone. It needs a doctor's supervision, and people with estrogen-sensitive cancers must not use it without medical approval.

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