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    Glossary Keratinocyte Proliferation

    process where skin cells multiply to regenerate and heal

    Keratinocyte proliferation refers to the process by which keratinocytes, the primary cells in the outer layer of the skin, multiply and produce new cells. This process is crucial for skin regeneration and healing, as it helps replace dead or damaged skin cells and maintain the skin's protective barrier. For professionals, understanding keratinocyte proliferation is essential for studying skin conditions and developing treatments for disorders like psoriasis and alopecia.

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    1. Indications for a brain‐hair follicle axis: inhibition of keratinocyte proliferation and up‐regulation of keratinocyte apoptosis in telogen hair follicles by stress and substance P The FASEB Journal · 2001 · 125 citations
    2. p63 Regulates Human Keratinocyte Proliferation via MYC-regulated Gene Network and Differentiation Commitment through Cell Adhesion-related Gene Network Journal of Biological Chemistry · 2011 · 82 citations
    3. Differential effects of caffeine on hair shaft elongation, matrix and outer root sheath keratinocyte proliferation, and transforming growth factor‐β2/insulin‐like growth factor‐1‐mediated regulation of the hair cycle in male and female human hair follicles<i>in vitro</i> British Journal of Dermatology · 2014 · 60 citations
    4. Reciprocal role of vitamin D receptor on β-catenin regulated keratinocyte proliferation and differentiation The Journal of Steroid Biochemistry and Molecular Biology · 2013 · 49 citations
    5. The TFIID subunit TAF4 regulates keratinocyte proliferation and has cell-autonomous and non-cell-autonomous tumour suppressor activity in mouse epidermis Development · 2007 · 28 citations
    6. Expression of<i>Sfrp2</i>Is Increased in Catagen of Hair Follicles and Inhibits Keratinocyte Proliferation Annals of Dermatology · 2014 · 25 citations
    7. WIF1 Is Expressed by Stem Cells of the Human Interfollicular Epidermis and Acts to Suppress Keratinocyte Proliferation Journal of Investigative Dermatology · 2013 · 18 citations
    8. Impaired Keratinocyte Proliferative and Clonogenic Potential in Transgenic Mice Overexpressing 14-3-3σ in the Epidermis Journal of Investigative Dermatology · 2011 · 15 citations
    9. Keratinocyte Growth Factor Modified Messenger RNA Accelerating Cell Proliferation and Migration of Keratinocytes Nucleic Acid Therapeutics · 2018 · 11 citations
    10. Norepinephrine Regulates Keratinocyte Proliferation to Promote the Growth of Hair Follicles Cells tissues organs · 2016 · 8 citations
    11. Impact of mTORC1 inhibition on keratinocyte proliferation during skin tumor promotion in wild‐type and BK5.Akt<sup>WT</sup> mice Molecular carcinogenesis · 2013 · 8 citations
    12. Differential effects of Wnt5a on the proliferation, differentiation and inflammatory response of keratinocytes Molecular Medicine Reports · 2017 · 6 citations
    13. Cyclin D3 deficiency inhibits skin tumor development, but does not affect normal keratinocyte proliferation Oncology Letters · 2017 · 2 citations
    14. 0843 N6-methyladenosine RNA modification promotes keratinocyte proliferation and cutaneous wound repair through regulation of MTOR stability Journal of Investigative Dermatology · 2025 · 1 citations
    15. Hair Growth Promoting Effects of Kesh-Kanti-Expert-Oil are Mediated Through Keratinocyte Proliferation and Modulation in Follicular Microenvironment Pharmacological Research - Natural Products · 2025
    16. The involvement of Elf5 in regulating keratinocyte proliferation and differentiation processes in skin PLoS ONE · 2025
    17. 085 Dermal papilla cells control hair follicle matrix keratinocytes proliferation through versican Journal of Investigative Dermatology · 2024
    18. 854 Dermal fibroblasts enhance growth factors production by androgens, and modulate keratinocyte proliferation and differentiation 2018
    19. Latanoprost-Loaded Nanotransfersomes Designed for Scalp Administration Enhance Keratinocytes Proliferation Molecular Pharmaceutics · 2022
    20. Xenobiotics in Vitro: The Influence ofL-Cystine, Pantothenat, and Miliacin on Metabolic and Proliferative Capacity of Keratinocytes Cutaneous and ocular toxicology · 2006 · 9 citations
    21. 1433 Role of BNC1 in keratinocytes proliferation and migration: A critical regulator of wound healing? Journal of Investigative Dermatology · 2018
    22. Proliferation and Differentiation of Cultured Human Keratinocytes is Modulated by 1,25(OH)<sub>2</sub>D<sub>3</sub> and Synthetic Vitamin D<sub>3</sub> Analogues in a Cell Density‐, Calcium‐ and Serum‐Dependent Manner* Pharmacology & toxicology · 1997 · 39 citations
    23. Biphasic Effects of Minoxidil on the Proliferation and Differentiation of Normal Human Keratinocytes Skin Pharmacology and Physiology · 2009 · 34 citations
    24. Physiological and retinoid-induced proliferations of epidermis basal keratinocytes are differently controlled EMBO journal · 2002 · 127 citations
    25. Evaluation of Keratinocyte Proliferation and Differentiation in Vitamin D Receptor Knockout Mice* Endocrinology · 2000 · 114 citations
    26. Evaluation of Keratinocyte Proliferation and Differentiation in Vitamin D Receptor Knockout Mice Endocrinology · 2000 · 29 citations
    27. Decorin promotes proliferation and migration of ORS keratinocytes and maintains hair anagen in mice Experimental Dermatology · 2018 · 10 citations
    28. Abstract 5357: Targeting mTORC1 suppresses proliferation of keratinocyte stem cells and inhibits skin tumor promotion in mice Cancer research · 2014
    29. L-Cystine-Containing Hair-Growth Formulation Supports Protection, Viability, and Proliferation of Keratinocytes Clinical, Cosmetic and Investigational Dermatology · 2020 · 2 citations
    30. Sulfated hyaluronan‐containing artificial extracellular matrices promote proliferation of keratinocytes and melanotic phenotype of melanocytes from the outer root sheath of hair follicles Journal of Biomedical Materials Research Part A · 2019 · 8 citations