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    The Involvement of Elf5 in Regulating Keratinocyte Proliferation and Differentiation Processes in Skin

    January 2025 in “ PLoS ONE ”
    Anhua Hu, Maximilian E. Pickup, Maryam A. Lawal … Mohammed I. Ahmed
    Studysummary This study identified the transcription factor Elf5 as a novel regulator of keratinocyte proliferation and differentiation in skin, with expression elevated in stem/progenitor cell populations, suggesting its potential role in determining cell fate during skin and hair development.
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    Research cited in this study 12

    1. MicroRNA-148a Controls Epidermal and Hair Follicle Stem/Progenitor Cells by Modulating the Activities of ROCK1 and ELF5 ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2022
    2. Thy1 Marks a Distinct Population of Slow-Cycling Stem Cells in the Mouse Epidermis Nature communications · 2022
    3. Interplay of MicroRNA-21 and SATB1 in Epidermal Keratinocytes During Skin Aging Journal of Investigative Dermatology · 2019
    4. Isolating Hair Follicle Stem Cells and Epidermal Keratinocytes from Dorsal Mouse Skin Journal of Visualized Experiments · 2016
    5. MicroRNA-214 Controls Skin and Hair Follicle Development by Modulating the Activity of the Wnt Pathway Journal of Cell Biology · 2014
    6. Markers of Epidermal Stem Cell Subpopulations in Adult Mammalian Skin Cold Spring Harbor Perspectives in Medicine · 2014
    7. P63 Regulates Satb1 to Control Tissue-Specific Chromatin Remodeling During Development of the Epidermis The Journal of Cell Biology · 2011
    8. Micro-RNA-31 Controls Hair Cycle-Associated Changes in Gene Expression Programs of the Skin and Hair Follicle ˜The œFASEB journal · 2010
    9. Epidermal Homeostasis: A Balancing Act of Stem Cells in the Skin Nature Reviews Molecular Cell Biology · 2009
    10. Epidermal Cells: Methods and Protocols Melanoma Research · 2005
    11. Molecular Principles of Hair Follicle Induction and Morphogenesis BioEssays · 2005
    12. Enrichment for Living Murine Keratinocytes from the Hair Follicle Bulge with the Cell Surface Marker CD34 Journal of Investigative Dermatology · 2003