8 citations
,
January 2014 in “BioMed Research International” This study reported that among three plant extracts tested for hair growth on nude mice, Eclipta alba significantly increased hair density and length, unlike Asiasari radix and Panax ginseng.
7 citations
,
August 2020 in “Plastic and reconstructive surgery. Global open” In this study, QR 678 and QR 678 Neo formulations containing growth factors and peptides were found to be safe in vitro and promoted hair growth in vivo in an animal model, suggesting their potential as treatments for alopecia, including secondary alopecia post-chemotherapy.
7 citations
,
August 2019 in “Aesthetic Plastic Surgery” Both surgical and non-surgical hair loss treatments lack a standard treatment plan and sufficient patient satisfaction data.
5 citations
,
July 2023 in “Frontiers in Veterinary Science” This study found that wounds in sheep treated with mesenchymal stem cells and platelet-rich plasma showed improved healing, reduced inflammation and contraction, and better skin structure compared to untreated wounds.
1 citations
,
January 2021 in “Acta Cirurgica Brasileira” This study found that both finasteride and dutasteride led to morphological and functional kidney damage in rats, with more severe effects observed in the dutasteride group.
1 citations
,
January 2018 in “Journal of V. N. Karazin Kharkiv National University: Series Medicine” This review analyzes studies on autologous platelet-rich plasma for androgenic alopecia, reporting mixed results and highlighting the need for standardized protocols and further research.
January 2025 in “Journal of Plastic Reconstructive & Aesthetic Surgery” Two L-PRP treatments improve hair density in mild to moderate alopecia.
July 2012 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” New treatment with Wnt proteins and growth factors safely increases hair thickness.
April 2013 in “Cancer Research” This study found that a botanical extract increased Bcl-2 levels and improved the anagen-to-telogen hair ratio in men with androgenetic alopecia, suggesting potential for managing chemotherapy-induced alopecia.
220 citations
,
June 2013 in “The Journal of Pathology” This study found that immune privilege collapse in the hair follicle bulge and associated immune responses may contribute significantly to the pathogenesis of lichen planopilaris, suggesting a potential autoimmune basis for the disease.
149 citations
,
June 2010 in “The FASEB journal” In this study, miR-31 was found to play a significant role in hair cycle regulation in mice by controlling key gene expressions involved in hair growth and differentiation.
124 citations
,
January 2012 in “Journal of Allergy and Clinical Immunology” This study found that activation of cannabinoid 1 receptors in human scalp hair follicles may limit excessive mast cell activation and maturation, suggesting a potential therapeutic strategy for managing MC-dependent skin diseases.
64 citations
,
October 2020 in “Journal of lasers in medical sciences” This review discusses the benefits and drawbacks of low-level laser therapy for various non-surgical conditions based on existing literature, but reports no new clinical findings and suggests further research is needed.
4 citations
,
July 2025 in “Frontiers in Pharmacology” This study found that cooling combined with antioxidants can improve scalp cooling effectiveness in preventing chemotherapy-induced alopecia by maintaining hair follicle viability and function.
2 citations
,
March 2023 in “Biomedicine & pharmacotherapy” This study found that platelet lysate significantly improved hair growth and follicle performance in both experimental settings and AGA patients, showing results comparable to platelet-rich plasma.
1 citations
,
September 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that miR-148a plays a significant role in regulating skin homeostasis and hair follicle cycling, influencing stem cell activity and development in mice.
81 citations
,
February 2016 in “Veterinary pathology” This review discusses the commonly observed pathological findings in progeroid mouse models and highlights the importance of understanding mouse strain backgrounds and progeria-related phenotypes for accurate pathology data interpretation.
43 citations
,
December 2006 in “The American journal of pathology” This study found that Edar signaling plays a role in regulating the hair cycle and apoptosis in hair follicle keratinocytes during the catagen phase in mice.
7 citations
,
December 2024 in “Journal of Functional Biomaterials” This review discusses the role of advanced platelet-rich fibrin (A-PRF) in oral and maxillofacial surgery, highlighting its potential benefits for healing, pain relief, and graft integration, with a need for more clinical trials to confirm long-term effects.
5 citations
,
October 2021 in “Frontiers in Cell and Developmental Biology” This study examined aging hair follicle stem cells in mice and found that inflammation reduction in dermal white adipose tissue can stimulate regenerative behavior, highlighting its role in hair follicle aging.
June 2023 in “International journal of molecular sciences” In this study, researchers observed that heat stress significantly affected hair and skin traits in two indigenous goat breeds, with Kodi Aadu goats demonstrating greater thermal resilience compared to Kanni Aadu goats, potentially due to differences in gene expression and methylation.
August 2022 in “Nutrients” This ex vivo study found that hair follicles in female pattern hair loss exhibited nutrient insufficiency and dormant metabolism, but maintained nutrient uptake capability, suggesting potential benefits of nutritional supplementation as an adjunct therapy.
151 citations
,
June 2010 in “Endocrinology and metabolism clinics of North America” This article compares two rare genetic diseases, vitamin D-dependent rickets type 1 and type 2, focusing on their similar presentations of hypocalcemia and rickets in infancy, but reports no new clinical results.
115 citations
,
August 2020 in “International Journal of Molecular Sciences” This systematic review indicates that a platelet-rich plasma concentration of 1.0 × 10^6 plt/μL may be optimal for tissue regeneration due to sufficient nutrition supply and effective growth factor diffusion in vivo.
42 citations
,
May 2016 in “American Journal of Clinical Dermatology” This review discusses the use of platelet-rich plasma for pattern hair loss treatment and examines existing clinical studies without presenting new clinical results.
36 citations
,
October 2009 in “Journal of biological chemistry/The Journal of biological chemistry” This study reports that TFM-4AS-1, a selective androgen receptor modulator, promoted bone and muscle growth with reduced effects on reproductive organs in ovariectomized rats.
18 citations
,
January 2019 in “International Journal of Trichology” This study found that PRP therapy resulted in better hair growth and patient satisfaction than minoxidil therapy in men with androgenetic alopecia over six months, and patients with higher platelet counts in PRP experienced greater improvement.
14 citations
,
May 2022 in “International Journal of Molecular Sciences” This study found that platelet-rich plasma therapy reduced inflammation and improved bladder function in a rat model of ketamine-induced ulcerative cystitis.
12 citations
,
January 2021 in “Springer eBooks” 6 citations
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August 2024 in “Biomacromolecules” This study introduces a novel in vitro model for clubfoot fibrosis to enable high-throughput drug screening and found that while the model increased collagen deposition, the antifibrotic drug minoxidil effectively inhibited the expression of collagen cross-linking enzymes.