Does Treatment with Dutasteride or Finasteride Have Impact on Renal Morphology? Experimental Study

    January 2021 in “ Acta Cirurgica Brasileira ”
    Marcello Muniz da Silva, J Estrada, Bianca Martins Gregório … Diogo O. Souza
    Studysummary This study found that both finasteride and dutasteride led to morphological and functional kidney damage in rats, with more severe effects observed in the dutasteride group.
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    Research cited in this study 5

    1. The Corpus Cavernosum After Treatment With Dutasteride or Finasteride: A Histomorphometric Study in a Benign Prostatic Hyperplasia Rodent Model Asian Journal of Andrology · 2018
    2. Finasteride Reduces Microvessel Density and Expression of Vascular Endothelial Growth Factor in Renal Tissue of Diabetic Rats The American Journal of the Medical Sciences · 2015
    3. Morphometric-Stereological and Functional Epididymal Alterations and a Decrease in Fertility in Rats Treated with Finasteride and After a 30-Day Post-Treatment Recovery Period Fertility and Sterility · 2012
    4. Effects of Finasteride on Vascular Endothelial Growth Factor Scandinavian Journal of Urology and Nephrology · 2002
    5. 5α-Reductase Activity in the Prostate Urology · 2001

    Related research 2

    1. The Preventive and Therapeutic Efficacy of Finasteride and Dutasteride in TRAMP Mice The FASEB Journal · 2013
    2. Comparative Effect of Finasteride and Dutasteride on Chromogranin A Levels Anticancer Research · 2010