Morphometric-Stereological and Functional Epididymal Alterations and a Decrease in Fertility in Rats Treated with Finasteride and After a 30-Day Post-Treatment Recovery Period

    April 2012 in “ Fertility and Sterility ”
    Patrick Garcia, Mainara Ferreira Barbieri, Juliana Elaine Perobelli, Sílvio Roberto Consonni, Suzana de Fátima Paccola Mesquita, Wilma De Grava Kempinas, Luis S. Pereira
    Image of study
    TLDR Finasteride causes lasting fertility decrease in rats.
    The study investigated the effects of finasteride on the epididymis and fertility in rats. The results showed that finasteride treatment caused morphometric-stereological and functional alterations in the epididymis, leading to a decrease in fertility. These effects persisted even after a 30-day post-treatment recovery period. The study suggests that finasteride may have negative effects on male reproductive health and fertility.
    Discuss this study in the Community →

    Research cited in this study

    14 / 14 results

    Related Community Posts Join

    6 / 1000+ results

      community Quit vaping/smoking = 80% less loss

      in Research/Science  235 upvotes 8 months ago
      Quitting vaping significantly reduced hair loss for a user who was a heavy vaper and also taking finasteride. Some participants suggest nicotine's vasoconstrictive properties may worsen hair loss, while others share personal anecdotes of hair improvement after quitting smoking or vaping.

      community Topical fin formulation question

      in Finasteride  91 upvotes 1 week ago
      A user is making a homemade topical finasteride solution by dissolving crushed finasteride tablets in ethanol and PG. They are unsure if the final solution maintains the intended concentration after filtering and are considering adding more ethanol to ensure accuracy.

      community Topical finasteride carrier/vehicle

      in Finasteride  135 upvotes 3 weeks ago
      The user is considering making a homemade topical finasteride solution using an ethanol-based carrier. They are inquiring if a solution containing partially denatured ethyl alcohol and benzalkonium chloride is suitable.

      community Chest discomfort on finasteride?

      in Finasteride  72 upvotes 3 months ago
      A user experienced chest discomfort after taking finasteride for hair loss and is concerned about whether it is a side effect or an allergy. They are advised to consult a doctor and consider other hair loss treatments if necessary.

    Related Research

    1 / 1 results