Platelet Lysate Promotes Hair Growth: In Vitro and In Vivo Mechanism and Randomized, Controlled Trial

    March 2023 in “ Biomedicine & pharmacotherapy
    Qing Guan, Zehong Guo, Damao Dai, Zhexiang Fan, Jian Chen, Shulin Wu, Xiaomin Liu, Yong Miao, Zhiqi Hu, Qian Qu
    Image of study
    TLDR Platelet lysate effectively promotes hair growth and improves hair thickness in people with androgenetic alopecia.
    The study investigated the effects of platelet lysate (PL) on hair growth using in vitro and in vivo models, and a randomized, controlled, double-blind clinical trial with 107 androgenic alopecia (AGA) patients. PL significantly promoted hair growth, prolonged the anagen phase, and reduced inflammatory markers. Clinically, PL improved hair diameter, hair counts, and anagen hair counts over 6 months without side effects. The study concluded that PL is an effective and standardized treatment for AGA, comparable to platelet-rich plasma (PRP), due to its regenerative and anti-inflammatory properties.
    Discuss this study in the Community →

    Research cited in this study

    26 / 26 results

    Related Community Posts Join

    6 / 77 results

      community New and Interesting HairLoss Studies/Papers/Reviews

      in Treatment  42 upvotes 4 years ago
      Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

      community Thoughts on platelet-rich plasma therapy

      in Treatment  3 upvotes 1 month ago
      Platelet-rich plasma (PRP) therapy for hair loss is expensive, painful, and often ineffective, with mixed reviews on its benefits. Alternatives like minoxidil, finasteride, and hair transplants are suggested as more reliable options.

      community Platelet rich plasma treatment

      in Treatment  4 upvotes 8 months ago
      A 27-year-old male experienced rapid hair loss after dengue fever, which activated a balding gene. The doctor suggested platelet-rich plasma treatment for hair regrowth.

      community platelet rich plasma experiences/thoughts?

      in Treatment  3 upvotes 2 years ago
      Hair loss discussion includes treatments like Minoxidil, finasteride, and RU58841. Platelet rich plasma treatment is considered expensive but cheaper than hair transplant.

      community PRP ( PLATELET-RICH-PlASMA) for hair loss

      in Treatment  1 upvotes 1 year ago
      A 27-year-old male experiencing hair loss post-Covid is considering PRP (platelet-rich plasma) therapy. He's seeking personal experiences about the process, particularly regarding pain levels, despite his dermatologist's assurance of using local anesthesia.

    Related Research

    8 / 8 results