Platelet Lysate Promotes Hair Growth: In Vitro and In Vivo Mechanism and Randomized, Controlled Trial

    March 2023 in “ Biomedicine & pharmacotherapy
    Qing Guan, Zehong Guo, Damao Dai, Zhexiang Fan, Jian Chen, Shulin Wu, Xiaomin Liu, Yong Miao, Zhiqi Hu, Qian Qu
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    TLDR Platelet lysate effectively promotes hair growth and improves hair thickness in people with androgenetic alopecia.
    The study investigated the effects of platelet lysate (PL) on hair growth using in vitro and in vivo models, and a randomized, controlled, double-blind clinical trial with 107 androgenic alopecia (AGA) patients. PL significantly promoted hair growth, prolonged the anagen phase, and reduced inflammatory markers. Clinically, PL improved hair diameter, hair counts, and anagen hair counts over 6 months without side effects. The study concluded that PL is an effective and standardized treatment for AGA, comparable to platelet-rich plasma (PRP), due to its regenerative and anti-inflammatory properties.
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