Platelet Lysate Promotes Hair Growth: In Vitro and In Vivo Mechanism and Randomized, Controlled Trial

March 2023 in “ Biomedicine & pharmacotherapy ”

Qing Guan, Zehong Guo, Damao Dai, Zhexiang Fan, Jian Chen, Shulin Wu, Xiaomin Liu, Yong Miao, Zhiqi Hu, Qian Qu

platelet lysate androgenic alopecia anagen phase inflammatory markers hair diameter hair counts anagen hair counts platelet-rich plasma PL AGA PRP

TLDR Platelet lysate effectively promotes hair growth and improves hair thickness in people with androgenetic alopecia.

The study investigated the effects of platelet lysate (PL) on hair growth using in vitro and in vivo models, and a randomized, controlled, double-blind clinical trial with 107 androgenic alopecia (AGA) patients. PL significantly promoted hair growth, prolonged the anagen phase, and reduced inflammatory markers. Clinically, PL improved hair diameter, hair counts, and anagen hair counts over 6 months without side effects. The study concluded that PL is an effective and standardized treatment for AGA, comparable to platelet-rich plasma (PRP), due to its regenerative and anti-inflammatory properties.

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Research cited in this study

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