Identification of Anabolic Selective Androgen Receptor Modulators with Reduced Activities in Reproductive Tissues and Sebaceous Glands
October 2009
in “
Journal of biological chemistry/The Journal of biological chemistry
”
selective androgen receptor modulators SARMs TFM-4AS-1 FTBU-1 androgen receptor partial agonist non-steroidal SARM 5α-reductase inhibition anabolic effects bone growth muscle growth prostate growth seminal vesicle growth ovariectomized rats reproductive organs sebaceous glands 5-alpha-reductase inhibition
Studysummary This study reports that TFM-4AS-1, a selective androgen receptor modulator, promoted bone and muscle growth with reduced effects on reproductive organs in ovariectomized rats.
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