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research Effect of Saw Palmetto Supplements on Androgen-Sensitive LNCaP Human Prostate Cancer Cell Number and Syrian Hamster Flank Organ Growth

6 citations , January 2016 in “Evidence-based complementary and alternative medicine”

In this study, saw palmetto supplements showed varied effects on cell growth in vitro and did not significantly inhibit growth in the hamster flank organ model despite a notable trend.

research Activated Polyamine Catabolism Depletes Acetyl-CoA Pools and Suppresses Prostate Tumor Growth in TRAMP Mice

91 citations , July 2004 in “Journal of Biological Chemistry”

This study found that overexpression of the enzyme SSAT in a mouse model significantly reduced prostate tumor size and progression, suggesting it could be a promising strategy against prostate cancer.

research Expression and Cellular Localization of Keratinocyte Growth Factor and Its Receptor in Human Hyperplastic Prostate Tissue¹

4 citations , June 1998 in “The Journal of Clinical Endocrinology & Metabolism”

This study found that keratinocyte growth factor is a potent mitogen in human hyperplastic prostate cells, suggesting it plays an important role in prostate growth by acting in a paracrine manner.

research Prostate-Sparing Effects in Primates of the Potent Androgen 7α-Methyl-19-Nortestosterone: A Potential Alternative to Testosterone for Androgen Replacement and Male Contraception1

14 citations , December 1998 in “The Journal of Clinical Endocrinology and Metabolism”

This study found that MENT is 10 times more potent than testosterone in suppressing gonadotropins and contributing to anabolism in monkeys, with a potentially wider therapeutic index for human androgen replacement and male contraception.

research Potential roles of FGF5 as a candidate therapeutic target in prostate cancer.

2 citations , January 2023 in “PubMed”

This review discusses the potential role of FGF5 as a therapeutic target in prostate cancer and other conditions but reports no new results, highlighting a need for further research on FGF5 inhibitors.

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Community Join

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community Did anybody use beta sisterol for hair loss? I saw in many articles in the internet that said that beta sisterol blocks dht by inhibiting 5a reductase type 2 enzyme and some reviews of people who said that it worked better than saw palmetto in terms of stoping hair loss and helping prostate.

in Research/Science 9 upvotes 3 years ago

Beta-sitosterol may inhibit 5-alpha reductase type 2 enzyme, potentially reducing DHT levels and promoting hair growth, similar to finasteride but possibly with fewer side effects. Its effectiveness and side effects compared to other treatments like saw palmetto and finasteride remain uncertain due to limited research.

community Research: Minoxidil grows hair by suppressing androgen activity (DHT) in hair follicles.

43 upvotes 6 years ago

Minoxidil may suppress androgen activity in hair follicles, potentially aiding in hair growth and prostate cancer treatment. Users discuss the effectiveness of minoxidil and finasteride for hair maintenance and regrowth, with some preferring topical applications over oral due to safety concerns.

community Dutasterid per Fragebogen in Deutschland?

in Finasteride/Dutasteride 5 upvotes 2 months ago

The conversation discusses the high cost and process of obtaining Dutasteride in Germany, with users sharing alternatives and experiences. OP uses Dutasteride for prostate health and beard growth reduction, not for hair loss.

community Body hair growth on finasteride

in Finasteride/Dutasteride 2 upvotes 5 months ago

Finasteride can increase body and facial hair growth due to increased testosterone, despite its intended use to reduce hair loss on the scalp. Some users consider trying topical finasteride for less systemic impact, while others report mixed results and side effects.

community Life Extension - Hair Growth for Men

1 year ago

A new supplement for hair growth combines black rice, prickly pear, and saw palmetto, showing promising results in increasing hair density and reducing hair loss. The supplement is considered a drug-free alternative to traditional treatments like minoxidil and finasteride.

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Learn

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learn tamsulosin

Can tamsulosin affect hair growth when taken orally or applied topically? No trial has tested tamsulosin, oral or topical, for hair growth. The drug is approved only for urinary symptoms of an enlarged prostate, and there is no evidence it treats hair loss.

learn Vitamin E

What does Vitamin E do for hair growth and scalp health? One small trial (38 people) of oral tocotrienols, a form of vitamin E, reported more hairs; there is no independent confirmation. High-dose vitamin E carries bleeding and prostate-cancer risks.

learn Bicalutamide

Nonsteroidal anti-androgen, originally a prostate cancer drug

learn Cyproterone

a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor

learn Mesotherapy

Injections of drug or vitamin mixtures into the scalp

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