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This study found that millimolar concentrations of minoxidil in the skin induced VEGF production through HIF-1 stabilization by inhibiting PHD-2, implying a molecular mechanism for hair growth promotion.

This study demonstrated that caffeine, minoxidil, and the HIF-1α-stimulating agent deferiprone significantly enhanced dermal papilla cell proliferation in a 3D culture model, suggesting deferiprone as a potential alternative to minoxidil.

Caffeine can damage hearing cells and affect hearing recovery after ear trauma.

This study observed that deleting ARNT in keratinocytes of mice reduced zigzag hair production and altered hair follicle differentiation, likely by affecting the expression of specific cyclin-dependent kinase inhibitors.

This study found that a hypoxic microenvironment enhanced the proliferation and pluripotency of adipose mesenchymal stem cells, promoting hair follicle formation and upregulating specific growth factors in Arbas Cashmere goats.

This study found that bacterially induced metabolic changes in stem cells can enhance skin and hair follicle regeneration in both mice and humans, suggesting potential strategies for improving recovery after injury.

In this study, researchers found that stabilizing the protein HIF1A in hair follicles promotes glycolysis over oxidative phosphorylation, potentially reducing oxidative stress and supporting hair growth.

In this study, lipid metabolism was found to be reduced in scalp tissues of patients with androgenetic alopecia, and lipid supplementation enhanced hair growth-related gene expression in human dermal papilla cells, suggesting a potential role for lipids in promoting hair growth through HIF-1 signaling.

This study found that lipid supplementation can enhance hair growth by promoting trichogenic gene expression and proliferation of human dermal papilla cells, suggesting lipids as a potential therapeutic target for treating hair loss through HIF-1 signaling pathways.

This study investigated the potential mechanisms of Curcuma aeruginosa in treating androgenetic alopecia and identified 66 bioactive compounds interacting with proteins involved in the disorder, suggesting its involvement in hormone response and specific signaling pathways.

This study found that 1,25-dihydroxyvitamin D3 promotes hair growth and regeneration in mice by prolonging the anagen phase and counteracting DHT's inhibitory effects, suggesting its potential therapeutic role for androgenetic alopecia.

This study found that depletion of KRT17 in endometrial cancer reduced cell growth, motility, and angiogenesis, suggesting KRT17 as a potential therapeutic target.

This study found that stabilizing HIF1A in hair follicle cells promoted a shift to glycolysis, potentially reducing oxidative stress and promoting hair growth, particularly in balding dermal papilla cells.

In this study, transient transfection of the HIF-1α gene into fibroblasts led to increased VEGF expression, which may enhance the growth and anagen phase of human hair follicles in vitro.

Stabilizing HIF1A in hair follicles may boost hair growth by enhancing energy production and blood vessel formation.

This study found that overexpression of erythropoietin disrupted hair growth in mice by affecting dermal fat lipogenesis and lipolysis, leading to poor hair follicle development and truncal alopecia.

This study identified that bacterially-induced metabolic changes in keratinocytes enhance skin and hair follicle regeneration, suggesting that modifying skin microbiome interactions may improve wound healing.

This study found that dexpanthenol treatment reduced inflammation, oxidative stress, and apoptosis in rats, providing a protective effect against lipopolysaccharide-induced cardiac and endothelial damage.

This study found that an aqueous extract of Bacopa procumbens improved motor function and preserved neuronal structure in a mouse model of Parkinson's disease, suggesting its neuroprotective potential.

This review discusses the experimental targets of fetal wound healing and evaluates existing therapies for scarless healing in adult skin, but reports no new research findings.

This review discusses various gene therapy and non-viral delivery methods to promote angiogenesis for chronic wound healing, but it reports no new clinical results.

This research suggests that targeting the HIF-1α pathway via PHD inhibitors may enable regeneration similar to amphibians in mammals, potentially fast-tracking regenerative therapies from mice to humans.

This review discusses the role of lysophosphatidic acid in skin physiology and pathology, highlighting its significance in processes like wound healing and hair follicle development, but reports no new clinical findings.

This study found that HIF1 and mTORC1 signalling were active in both basal cell carcinoma and trichoepithelioma, but the pathways do not reliably differentiate between the two.

This study identified seven genes that may serve as biomarkers for diagnosing skin cutaneous melanoma by analyzing the relationship between UV exposure, ferroptosis, and the cancer's pathology.

In this study, a microneedle patch containing conditioned media from hypoxia-pretreated stem cells enhanced hair regeneration in an androgenetic alopecia mouse model by boosting perifollicular vascularization and hair follicle stem cell activation compared to minoxidil.

In this study, hUCMSCs-Exo significantly accelerated wound healing in rat perianal fistulas with notable safety, potentially through the activation of the HIF-1α/TGF-β/Smad signaling pathway.

In this study, topical quercetin was found to stimulate hair follicle growth and promote microvascular regrowth in mice, suggesting its potential for hair regrowth strategies.

This study found that applying a combination of pyridine‐2, 4‐dicarboxylic acid diethyl ester and resveratrol significantly increased hair density in Caucasian women after 1.5 months, potentially due to their synergistic effect on the HIF‐1α pathway.

This study found that stem cell factor (SCF) improved wound healing in diabetic mice by enhancing stem cell recruitment and increasing key protein expressions involved in the healing process.