April 2024 in “Dermatologic surgery” This source does not report specific results or findings, instead it provides details about the affiliation of the researchers and reference details for the publication.
February 2026 in “Archives of Dermatological Research” In this study, microneedle-assisted delivery of polyglutamate significantly improved hair parameters, scalp symptoms, and quality of life in androgenetic alopecia patients, with no serious adverse reactions reported.
In a rodent study, a flexible, self-powered triboelectric nanogenerator wound patch combining electrostimulation and photothermal effects was found to efficiently accelerate wound healing and hair follicle regeneration.
21 citations
,
June 2022 in “Pharmaceutics” This study found that bioactive extracts from goat placenta, particularly when delivered via dissolving microneedles, enhanced fibroblast proliferation and skin regeneration without being toxic to skin cells, suggesting a promising dermal application for improving skin health.
108 citations
,
August 2017 in “Clinical, Cosmetic and Investigational Dermatology” This review highlights microneedling's promise as an adjuvant therapy for enhanced drug delivery in dermatology, especially for conditions like atrophic scars and pigmentation disorders, though its efficacy for vitiligo is limited.
4 citations
,
July 2021 in “Journal of dermatology & dermatologic surgery” This review discusses the use of microneedling with a dermaroller for treating acne scars, hair loss, and wrinkles, and reports no new clinical results.
This study found that a bioorthogonal microneedle patch delivering AAV-aFGF effectively improved hair follicle regeneration and sustained hair growth in murine alopecia models compared to other methods.
106 citations
,
January 2016 in “Journal of Cosmetic Dermatology” This study found that adding platelet-rich plasma to microneedling improved outcomes for atrophic acne scars more than microneedling alone, according to both quantitative and qualitative assessments.
23 citations
,
September 2018 in “Dermatologic Therapy” This article explains that skin microneedling promotes skin regeneration by creating microinjuries, which stimulate collagen and elastin production, making it effective for treating various skin issues with high effectiveness, limited side effects, and a short recovery time.
April 2019 in “Lincoln (University of Nebraska)” This study engineered a programmable platform using miniaturized needle arrays for drug delivery, showing improved wound healing outcomes in diabetic mice compared to standard topical treatments.
This study developed a directional pressure-pump hydrogel delivery platform that enhances wound healing in diabetic mechanically dynamic wounds by targeting antibacterial agents and nanozymes directly to the lesion site, disrupting biofilms, mitigating tissue damage, and supporting proper skin closure and vascular remodeling in animal models.
October 2022 in “Skin appendage disorders” This study found that isolated scalp microneedling did not improve scalp coverage or hair density in male pattern hair loss patients, with no adverse events reported.
April 2020 in “Journal of The American Academy of Dermatology” This letter highlights concerns about transient lymphadenopathy as a potential adverse effect of platelet-rich plasma combined with microneedling for alopecia, emphasizing the need to understand its underlying cause.
In this chapter, the authors discuss how microneedling and platelet-rich plasma are effective for cosmetic purposes with minimal downtime, noting potential mild side effects and the necessity for multiple treatments.
November 2023 in “International Journal of Pharmaceutics” This study found that a new transdermal drug delivery system using globefish skin collagen peptides and dissolving microneedles effectively promoted hair regrowth in mice with androgenetic alopecia by reducing inflammation and enhancing vascularization.
October 2022 in “The Egyptian Journal of Hospital Medicine” This review discusses the potential role of microneedling in dermatology, particularly as an adjunct treatment for androgenic alopecia, and reports no new clinical results; it highlights mostly positive outcomes from existing studies.
August 2025 in “Frontiers in Microbiology” This study found that microneedling treatment improved hair regeneration in an animal model of alopecia areata and positively influenced the gut microbiome by restoring microbial diversity and altering short-chain fatty acid levels.
10 citations
,
May 2020 in “Journal of Dermatological Treatment” This study found that combining microneedling with 5% minoxidil improved hair growth in Chinese men with androgenetic alopecia, possibly through activating the Wnt/β-catenin signaling pathway.
July 2026 in “European Journal of Plastic Surgery” This study found that combining needle-free intradermal minoxidil delivery with standard topical minoxidil therapy improved early hair growth parameters and satisfaction in women with early-stage female pattern hair loss compared to topical therapy alone, with no serious adverse events reported over the 10-week period.
January 2024 in “Journal of Cosmetics, Dermatological Sciences and Applications” This study found that electronically-operated pneumatic injections for administering a peptide-hyaluronic acid combination were well tolerated and led to significant improvement in hair density and thickness for men with androgenic alopecia over six months, though the exact mechanism remains uncertain.
5 citations
,
January 2018 in “PubMed” In this study, applying a biodegradable microneedle patch after topical steroid application significantly increased steroid penetration and improved treatment outcomes in patients with prurigo nodularis compared to the control.
September 2025 in “PubMed” January 2016 in “Hair transplant forum international” Microneedling shows promise for hair growth but needs more research.
119 citations
,
December 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, transcutaneously applied nanoparticles and viral vectors were shown to penetrate murine hair follicles, internalize in antigen-presenting cells, and induce immune responses, suggesting a promising approach for vaccine delivery.
58 citations
,
December 2017 in “Journal of The European Academy of Dermatology and Venereology” This review highlights that microneedling shows some promise for improving hair growth in alopecia, particularly when used with other treatments, though more research is needed to establish its efficacy and protocols.
3 citations
,
March 2020 in “Our Dermatology Online” In this case series from Nepal, microneedling in combination with oral finasteride and minoxidil was associated with moderate to significant hair growth improvement in androgenetic alopecia patients, with high satisfaction and no complications reported.
Results are not reported in this abstract, but it outlines the objective to evaluate the efficacy of microneedling, alone and in combination with other treatments, for pattern hair loss through a systematic review and meta-analysis.
24 citations
,
January 2019 in “Journal of Cosmetic Dermatology” In this study, the authors reported that among patients with androgenetic alopecia, treatment with minoxidil 5% lotion combined with PRP and microneedling resulted in better hair growth and higher satisfaction compared to other treatment groups.
August 2023 in “Journal of controlled release” This research found that STAR particles, ceramic particles with microneedles, significantly enhance skin permeability and improve the topical delivery of drugs like minoxidil and acyclovir, effectively promoting or inhibiting hair growth without causing skin irritation in ex vivo pig skin and rat models.
November 2022 in “Clinical, Cosmetic and Investigational Dermatology” In this study, a combined treatment for moderate to severe androgenetic alopecia using electric microneedles showed a 100% response rate after 12 weeks, with improvements in hair density and mild side effects, offering promising application prospects.