Is Skin Microneedling a Good Alternative Method for Various Skin Defects Removal

September 2018 in “ Dermatologic Therapy ”

Kamila Zduńska, Anna Kołodziejczak, Helena Rotsztejn

microneedling collagen elastin alopecia minoxidil melasma tranexamic acid vitiligo 5-fluorouracil tacrolimus trichloroacetic acid peels platelet-rich plasma Rogaine PRP

From the encyclopedia

Microneedling →

technique to create small wounds in skin to activate collagen production and hair growth

collagen →

Minoxidil →

An essential vasodilator with some anti-androgenic effects

Studysummary This article explains that skin microneedling promotes skin regeneration by creating microinjuries, which stimulate collagen and elastin production, making it effective for treating various skin issues with high effectiveness, limited side effects, and a short recovery time.

Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer

The document from 2018 reviews the effectiveness of skin microneedling for treating various skin conditions, including photoaging, scars, pigmentation changes, and alopecia. Microneedling stimulates collagen and elastin production and can be enhanced by combining it with other treatments. Studies showed significant improvements in skin conditions with microneedling, such as a reduction in wrinkles, improved skin elasticity, and better outcomes for stretch marks and alopecia when combined with minoxidil, with 82% of subjects reporting over 50% improvement. Microneedling also showed promise in treating melasma and vitiligo, with one study reporting a 44.41% improvement in melasma when combined with tranexamic acid. A study on vitiligo with 25 patients found it effective when combined with 5-fluorouracil or tacrolimus. For dark circles and acne scars, combining microneedling with other treatments like trichloroacetic acid peels or platelet-rich plasma (PRP) showed significant aesthetic improvements. The document concludes that microneedling is a safe and effective method for skin defect treatment with minimal side effects, although long-term effects are unknown and proper aftercare is necessary.

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Research cited in this study

7 / 7 results

A Comparative Study of Microneedling with Platelet-Rich Plasma Plus Topical Minoxidil (5%) and Topical Minoxidil (5%) Alone in Androgenetic Alopecia

research A Comparative Study of Microneedling with Platelet-Rich Plasma Plus Topical Minoxidil (5%) and Topical Minoxidil (5%) Alone in Androgenetic Alopecia

48 citations , January 2017 in “International Journal of Trichology”

This study found that combining microneedling with PRP and topical minoxidil (5%) significantly improved hair growth in men with androgenetic alopecia compared to using minoxidil alone.

research Treating Alopecia Areata: Current Practices Versus New Directions

26 citations , October 2016 in “American journal of clinical dermatology”

New treatments like JAK inhibitors show promise for reversing alopecia areata.

Combined Autologous Platelet-Rich Plasma with Microneedling Versus Microneedling with Distilled Water in the Treatment of Atrophic Acne Scars: A Concurrent Split-Face Study

research Combined Autologous Platelet-Rich Plasma with Microneedling Versus Microneedling with Distilled Water in the Treatment of Atrophic Acne Scars: A Concurrent Split-Face Study

106 citations , January 2016 in “Journal of Cosmetic Dermatology”

This study found that adding platelet-rich plasma to microneedling improved outcomes for atrophic acne scars more than microneedling alone, according to both quantitative and qualitative assessments.

research Microneedle Applications in Improving Skin Appearance

131 citations , May 2015 in “Experimental Dermatology”

This review explores the development and cosmeceutical applications of microneedles for skin treatment, without reporting new clinical results, emphasizing safety and public perception as key factors for commercialization.

research Response to Microneedling Treatment in Men with Androgenetic Alopecia Who Failed to Respond to Conventional Therapy

68 citations , May 2015 in “Indian Journal of Dermatology”

This case series found that adding microneedling to conventional finasteride and minoxidil therapy for androgenetic alopecia improved new hair growth and patient satisfaction in poor responders.

research A Randomized Evaluator Blinded Study of Effect of Microneedling in Androgenetic Alopecia: A Pilot Study

136 citations , January 2013 in “International Journal of Trichology”

This study found that adding microneedling to minoxidil treatment significantly improved hair growth in men with androgenetic alopecia compared to minoxidil alone across all assessed measures.

research Mesotherapy: What Is New?

34 citations , December 2012 in “Indian Journal of Dermatology, Venereology and Leprology”

Mesotherapy shows promise for cellulite and facial rejuvenation but has mixed results for body sculpting and hair loss, with more research needed for safety and effectiveness.