Microneedle Applications in Improving Skin Appearance

The document from 2015 reviews the use of microneedles (MNs) in the cosmetic industry for skin rejuvenation, highlighting their minimally invasive nature and ability to enhance the delivery of therapeutic molecules into the skin. It discusses the evolution of microneedling technologies, such as Dermaroller® and Dermapen®, and their applications in combating skin imperfections by inducing collagen and elastin expression. The review notes the positive public perception of MN devices, with 80% favorability in studies, but also raises concerns about safety and the potential for misuse, especially when combined with unlicensed topical products. It mentions the use of MNs in delivering cosmeceuticals like eflornithine cream and minoxidil, with a study showing improved hair growth when using a Dermaroller with minoxidil versus minoxidil alone. The document calls for further research and regulatory engagement to ensure the safe use of MN products, particularly with the emergence of new devices like LED MicroNeedling Rollers.