Recent Advances in Microneedling-Assisted Cosmetic Applications

Microneedling, a technique that creates micro-injuries to stimulate collagen and elastin production, has shown promise in various cosmetic applications such as acne scar treatment, skin rejuvenation, and hair loss. The technique enhances the skin's permeability to cosmetic agents, improving their effectiveness. The document discusses the use of dissolvable microneedles (MNs) loaded with various cosmetic agents, such as ascorbic acid, hyaluronic acid, retinoids, niacinamide, and peptides, which have shown efficacy in improving wrinkles and skin hyperpigmentation. Studies have shown that microneedling, when combined with other treatments like glycolic acid peel, platelet-rich plasma, or Jessner’s solution, can significantly improve acne scars, skin texture, and post-acne pigmentation. For hair loss, microneedling has been successful in stimulating hair growth, particularly in severe male and female alopecia. Despite some limitations, microneedling has shown promising results in various skin conditions and is expected to commercially boom worldwide. Future research should focus on exploring alternative materials with better mechanical properties and biocompatibility, and new fabrication methods for MNs.