TLDR Microneedling with platelet-rich plasma can cause temporary, painful lymph node swelling in some patients.
The authors report on two female patients who developed recurring transient lymphadenopathy (LAP) after microneedling with platelet-rich plasma (PRP) for androgenetic alopecia (AGA). The LAPs arose after the first or second session and recurred in the same pattern at every following treatment session. The authors suggest that the underlying cause of these acute, painful, yet transient LAPs occurring in a small number of patients after microneedling with PRP needs to be clarified. The role of infection seems unlikely in these cases due to rapid spontaneous regression.
3 citations,
August 2019 in “Journal of The American Academy of Dermatology” PRP with microneedling is generally safe but can cause minor side effects like scalp itching, temporary hair shedding, and swollen lymph nodes.
28 citations,
October 2017 in “Journal of Cosmetic and Laser Therapy” Combining electrodynamic microneedle with 5% minoxidil improves hair growth and reduces hair loss in Chinese men.
100 citations,
June 2011 in “Journal of The American Academy of Dermatology” 5% minoxidil foam once daily works as well as 2% minoxidil solution twice daily for female hair growth and is more convenient.
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7 citations,
September 2018 in “Journal of cosmetic dermatology” A patient had painful swollen lymph nodes after a cosmetic skin and hair treatment, suggesting doctors should warn about this risk.
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