Recurring Transient Lymphadenopathy After Microneedling With Platelet-Rich Plasma for Androgenetic Alopecia

April 2020 in “ Journal of The American Academy of Dermatology ”

Cemile Tuğba Altunel, A. Tülin Güleç

microneedling platelet-rich plasma androgenetic alopecia lymphadenopathy PRP AGA LAP

From the encyclopedia

Microneedling →

technique to create small wounds in skin to activate collagen production and hair growth

Platelet-Rich Plasma →

growth factors taken from your blood and injected into your scalp to stimulate hair

Studysummary This letter highlights concerns about transient lymphadenopathy as a potential adverse effect of platelet-rich plasma combined with microneedling for alopecia, emphasizing the need to understand its underlying cause.

Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer

The authors report on two female patients who developed recurring transient lymphadenopathy (LAP) after microneedling with platelet-rich plasma (PRP) for androgenetic alopecia (AGA). The LAPs arose after the first or second session and recurred in the same pattern at every following treatment session. The authors suggest that the underlying cause of these acute, painful, yet transient LAPs occurring in a small number of patients after microneedling with PRP needs to be clarified. The role of infection seems unlikely in these cases due to rapid spontaneous regression.

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Research cited in this study

3 / 3 results

research Adverse Effects of Platelet-Rich Plasma and Microneedling

3 citations , August 2019 in “Journal of The American Academy of Dermatology”

This study found that platelet-rich plasma with microneedling for hair loss was mostly well tolerated, but some patients experienced mild side effects like scalp itching, transient hair shedding, and lymphadenopathy.

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This study found that a once-daily 5% minoxidil topical foam is as effective as a twice-daily 2% minoxidil topical solution for hair growth in women with androgenetic alopecia, with fewer side effects and greater styling convenience.