Assessing the Efficacy of Automated Microneedling Monotherapy for Androgenetic Alopecia: A Comparison of 3 Different Depths

The study assessed the safety and efficacy of automated microneedling (MN) as a standalone treatment for androgenetic alopecia (AGA) by comparing three different needle depths (0.5, 1.0, and 1.5 mm). It included 45 patients (14 male, 31 female) with a mean age of 39.8 years, divided into three groups of 15 each. After six sessions over three months, all patients showed clinical improvement, with Group A (0.5 mm depth) showing the highest improvement (77.5% on a quartile scale), followed by Group B (1.0 mm depth) with moderate improvement (51.9%), and Group C (1.5 mm depth) with poor improvement (16.3%). Dermoscopic evaluation showed significant differences among the groups in hair count, diversity, yellow dots, and peripilar signs, with Group A generally showing the best results. The study concluded that MN at a depth of 0.5 mm is the most effective monotherapy for AGA among the depths tested.