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Glossary Peripilar Sign

small pigmented spots around hair follicles indicating inflammation

The Peripilar Sign refers to a specific clinical feature observed in some cases of hair loss, particularly in conditions like alopecia areata. It is characterized by the presence of small, pigmented spots or halos around the hair follicles, which can be seen under dermoscopy. This sign indicates inflammation around the hair follicles and can help dermatologists diagnose and assess the severity of hair loss conditions.

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5 / 546 results

research Histological features of peripilar signs associated with androgenetic alopecia

95 citations , January 2004 in “Archives of Dermatological Research”

This study found that peripilar signs on the scalp are linked to perifollicular lymphocytic infiltrates in early androgenetic alopecia, detectable even in areas with high hair density.

research Peripilar Sign in Androgenetic Alopecia: Does It Really Indicate Peripilar Infiltrate?

January 2024 in “Dermatology practical & conceptual”

In this study, researchers found that the peripilar sign in patients with androgenetic alopecia does not indicate perifollicular infiltrate but is more frequent in individuals with lighter skin types due to contrast with the skin.

research Clinical evaluation of alopecias using a handheld dermatoscope

66 citations , November 2011 in “Journal of The American Academy of Dermatology”

This study concluded that a polarized-light handheld dermatoscope attached to a digital camera is a practical and useful tool for diagnosing different types of alopecia.

research Value of trichoscopy versus trichogram for diagnosis of female androgenetic alopecia

45 citations , January 2012 in “International Journal of Trichology”

This study reported that trichoscopy is a more effective diagnostic tool than the trichogram for early diagnosis of FAGA, regardless of hair shaft diversity cut-off levels.

research Trichoscopic Findings of Hair Loss in Koreans

16 citations , January 2015 in “Annals of Dermatology”

In this study, trichoscopic features aiding differential diagnosis of alopecia in Korean patients were found to be similar to those in Caucasians, but pigment pattern frequencies differed due to racial characteristics.

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community The MPB itch aka DHT itch is very real.

in Chat 9 upvotes 3 years ago

Hair loss itch is caused by DHT attacking follicles and stimulating nerves. Finasteride users who respond well don't experience this itch.

community Reducing Fibrosis in Hair Loss: Topical Pirfenidone

59 upvotes 5 months ago

Topical pirfenidone is highlighted as an effective anti-inflammatory and anti-fibrotic treatment for hair loss, particularly in addressing perifollicular fibrosis, which may enhance the effectiveness of standard treatments like finasteride and minoxidil. The user also uses calcipotriol, MCT oil, ciclopirox shampoo, and benzoyl peroxide shampoo as part of their regimen.

community What do these pictures say about my hair and scalp if anything? Miniaturization, inflammation, etc.?

in Research/Science 74 upvotes 4 years ago

Hair loss and scalp issues, with people discussing possible treatments such as Nizoral shampoo, Minoxidil, neem oil, and finasteride.

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