Flexible Triboelectric Nanogenerator Patch for Accelerated Wound Healing Through the Synergy of Electrostimulation and Photothermal Effect

The study presents a flexible, self-powered triboelectric nanogenerator (TENG) wound patch designed to accelerate wound healing by combining electrostimulation and photothermal effects. The patch is made from a conductive hydrogel composed of polyacrylamide and polydopamine, enhanced with multi-walled carbon nanotubes, providing high conductivity, stretchability, and biocompatibility. In a rodent model with full-thickness dorsal skin wounds, the e-patch demonstrated effectiveness in promoting wound repair and hair follicle regeneration by reducing inflammation, enhancing collagen deposition, and supporting vascular regeneration and epithelialization. This innovative approach offers a promising method for improving wound healing processes.