25 citations
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January 2024 in “International Journal of Nanomedicine” The hydrogel is safe, reduces oxidation, and helps heal wounds effectively.
4 citations
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January 2022 in “Journal of Bioscience and Bioengineering” This study demonstrated that electrical stimulation via a polypyrrole-modified electrode enhanced trichogenic gene expression in human dermal papilla cells, leading to increased hair growth in a mouse model.
19 citations
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November 2022 in “Antioxidants” In this study, ginger peel polysaccharides modified with zinc reduced inflammation in zebrafish by altering cytokine expression, suggesting potential for treating chronic inflammation-related diseases.
8 citations
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February 2022 in “PLoS ONE” This study found that Bacillus subtilis strain Ydj3 significantly enhanced sweet pepper seed germination, fruit quality, and rhizosphere bacterial composition, including increased yield and vitamin C content, in a commercial greenhouse setting.
November 2025 in “Advanced Science” In this study, researchers found that a cold atmospheric plasma-activated hydrogel containing interleukin-2 significantly enhanced hair regeneration in a depilated mouse model, promoting larger hair follicles and faster hair growth phase transition, suggesting it as a potential treatment for hair loss.
527 citations
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December 2011 in “Proceedings of the National Academy of Sciences” This study found that dextran-based hydrogels promoted significant neovascularization and skin regeneration in mouse models of third-degree burns, without the need for additional growth factors or cells.
3 citations
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May 2025 in “Journal of Applied Polymer Science” This study developed a multifunctional, sprayable hydrogel with temperature responsiveness, showing strong antimicrobial properties against E. coli and S. aureus, antioxidant activity, and cytocompatibility, indicating potential for wound healing applications.
December 2025 in “Journal of Composites and Compounds” In this review, researchers explored the design of composite biomaterials for immunomodulation and their potential to influence immune cell behavior, which could be leveraged for treating diseases like cancer and improving tissue regeneration, while also addressing translational challenges such as biocompatibility and safety.
6 citations
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June 2022 in “Frontiers in Bioengineering and Biotechnology” This study found that a hydrogel containing icariin enhanced wound healing and hair-follicle regeneration in vivo by promoting M2 macrophage polarization and modulating the BMP pathway, with treated skin defects showing improved recovery and new hair follicle development compared to untreated defects.
118 citations
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April 2020 in “Stem Cell Research & Therapy” This study found that adipose-derived mesenchymal stromal cell secretome, particularly when preconditioned with IFNγ, significantly influences cell motility and anti-inflammatory responses, enhancing its potential as a regenerative therapy.
August 2023 in “International Journal of Molecular Sciences” In this study, researchers developed a new sodium alginate/chitosan/Zn2+ hydrogel that showed improved physical properties, antibacterial activity, and biocompatibility, and demonstrated enhanced wound healing and skin regeneration in an in vitro model.
August 2025 in “Rare Metals” In this study, carbon dots derived from metformin and dopamine (MD‐CDs) effectively promoted healing in bacterial-infected wounds by inhibiting infection, expediting inflammation-to-healing transition, enhancing cell proliferation and migration, and fostering collagen deposition and hair follicle regeneration.
8 citations
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March 2024 in “Regenerative Therapy” This study found that using uniform poly(lactic-co-glycolic) acid microspheres to deliver insulin-like growth factor 1 stabilizes the protein and enhances its sustained delivery, supporting stem cell functions comparably to traditional methods, and showing potential for tissue and organ regeneration.
32 citations
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June 2021 in “Frontiers in Pharmacology” This study reports that Cur@CMCTS-Tk hydrogel effectively accelerated wound healing and tissue regeneration in rats by scavenging excess reactive oxygen species and protecting human fibroblasts from oxidative damage.
November 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” In this study, researchers developed a hierarchically engineered microreactor that effectively combats infected wounds by releasing antimicrobials at acidic sites, eradicating MRSA while avoiding resistance, and enhancing tissue repair through immune system modulation.
17 citations
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January 2024 in “Journal of Materials Chemistry B” In this study, researchers developed a hyaluronic acid-coated copper peroxide nano-antimicrobial system that demonstrated precise antimicrobial activity and accelerated wound healing by releasing reactive oxygen species in response to bacterial enzymes, in both laboratory and animal tests.
October 2019 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study found that the developed hydrogel nanoparticles showed potential for enhancing hair growth by effectively delivering and releasing hair growth-promoting herbal extracts into hair follicles.
March 2025 in “Wound Repair and Regeneration” In a study using mouse models, researchers developed a gelatin methacryloyl scaffold with calcium-doped silica nanoparticles loaded with deferoxamine, which significantly improved skin flap survival and hair follicle growth, suggesting potential clinical applications in tissue regeneration.
This study highlights the successful design of recombinant fortilin constructs for potential drug development targeting atherosclerotic plaque formation in cardiovascular disease.
June 2026 in “Drug Delivery and Translational Research” This study developed a spring-driven microneedle booster that improved early and cumulative delivery of minoxidil, accelerating hair regrowth compared to traditional roller methods in an androgenetic alopecia model.
13 citations
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February 2023 in “Pharmaceutics” This review outlines strategies for regulating macrophage response using bioactive materials to enhance wound healing, focusing on extracellular matrix-based scaffolds and nanofibrous composites, but reports no new clinical results.
83 citations
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May 2021 in “Biomolecules” This study found that an injectable composite hydrogel containing cerium bioactive glass improved wound healing in diabetic rats by promoting angiogenesis and offering antibacterial properties, suggesting its potential for enhancing diabetic foot wound repair.
This study found that encapsulating dermal papilla spheroids in alginate hydrogel with extracellular matrix proteins increased alkaline phosphatase activity, suggesting an enhanced manipulation of dermal papilla activity.
In this study, researchers engineered extracellular vesicles enriched with functional mitochondria to enhance healing in diabetic wounds by reversing mitochondrial and immunometabolic dysfunction in macrophages.
1 citations
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March 2023 in “Colloids and surfaces. B, Biointerfaces” This study reports that a collagen scaffold with p-Coumaric acid showed promising wound-healing effects in diabetic wound models by enhancing tissue regeneration and balancing collagen turnover.
March 2026 in “Acta Histochemica” April 2019 in “Journal of Investigative Dermatology” This study developed an Asian human sebocyte cell line from breast skin tissue that can be used for sebaceous gland biology investigations, showing that Y27632 may promote cell growth through EGFR-CRAF-MEK-ERK and AKT pathways.
February 2024 in “Advanced Functional Materials” This study reported that a newly developed hydrogel patch, designed to recruit regulatory T cells through ROS-triggered release of CCL22, improved wound healing and hair follicle regeneration in a diabetic mouse model by scavenging ROS, thereby protecting Tregs and suppressing Th17 cells.
January 2005 in “Di-san junyi daxue xuebao” This study found that treatment with aerosol bioelectricity accelerated wound healing in burned rats by enhancing the expression of EGF and β_1 integrin in skin basal and hair follicle cells.
6 citations
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April 2022 in “Cellular and Molecular Life Sciences” This study reports that a new protocol using Angio PRP improved wound healing in mice by enhancing key healing processes and regulating inflammation, suggesting potential for clinical advancements.