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Gene therapy shows promise for enhancing physical traits but faces ethical, safety, and regulatory challenges.

This article discusses the potential benefits of GcMAF and oral MAF, developed by "Saisei Mirai", for cancer and other conditions, but reports no new clinical results.

This study found that multimetal starvation by the immune protein calprotectin triggers unique regulatory responses in Pseudomonas aeruginosa, beyond those seen with individual metal shortages.

This study found that PCL-Col/ZnO fibrous scaffolds enhanced wound healing and exhibited antibacterial properties, making them promising for use as a wound dressing.

In this study, PGD2 was shown to increase testosterone production in human keratinocytes through reactive oxygen species, suggesting potential benefits of antioxidants like N-acetyl-cysteine for AGA patients.

This study reported the establishment of a chemically defined culture system that supports tooth reconstitution and detailed how co-stimulation of specific signaling pathways can sustain tooth development stages and initiate enamel formation, providing insights into tooth regeneration mechanisms.

This study found that combining ultrasound with a GelMA hydrogel able to deliver mesenchymal stem cell-derived vesicles significantly improved wound healing in a mouse model by enhancing fibroblast activity, promoting re-epithelialization, and facilitating hair follicle regeneration, highlighting a novel approach to skin regeneration therapy.

This study demonstrated that a newly developed polypeptide-protein hydrogel with vascularization and antibacterial properties promoted tissue regeneration and hair follicle formation in infected wound healing.

In this in vitro study, simple centrifugation with calcium gluconate activation led to a significantly higher release of PDGF-BB in PRP compared to other methods, which may inform improved clinical PRP preparation protocols.

In this study, researchers developed a composite electrospun wound dressing containing strontium zinc silicon bioceramics, which significantly activated hair follicle stem cells and promoted hair follicle and capillary regeneration in deep burn wounds, suggesting a promising approach for burn wound healing.

This article reviews recent developments in microneedles combining metallic elements and herbal compounds for wound healing, highlighting their benefits such as enhanced therapeutic efficacy and reduced toxicity, and offering a reference for future advancements in this technology.

This study presents a new wireless bioelectronic system powered by ambient Wi-Fi signals that enhances wound healing by providing electrical stimulation and real-time monitoring, offering a promising solution for at-home treatment and regenerative therapy.

In this study, researchers developed a responsive bilayer hydrogel for diabetic wounds that delivers drugs and oxygen in sync with healing stages, achieving a 99.1% wound closure rate in 14 days by integrating anti-inflammatory, antibacterial, and anti-fouling functions.

This review explores how recombinant protein hydrogels, employing molecular engineering and crosslinking strategies, offer advanced applications in regenerative medicine by mimicking extracellular matrix dynamics and providing enhanced mechanical, environmental, and biological properties.

This study found that applying both dehydrothermal treatment and carbodiimide crosslinking improved the mechanical properties of porcine acellular dermal matrix scaffolds without added cytotoxicity, suggesting potential applications in tissue engineering.

In this study on a preclinical mice model, the researchers reported that a chitosan nanogel with Mn₃O₄ nanoparticles facilitated scarless wound healing by regulating reactive oxygen species and influencing signaling molecules throughout the healing stages.

In this study, researchers developed an acellular bioscaffold made from ovine tendon collagen with an antibacterial coating for treating skin wounds. They found that genipin crosslinking improves the scaffold's properties, and with plasma polymerisation, it enhances antibacterial activity, potentially benefiting wound healing.

This study demonstrated that a keratin gel promotes nerve regeneration across critical defects in rabbit models, showing improved nerve conduction and muscle action potential compared to control treatments.

This study found that using three-dimensional cell culture with Matrigel enhances the biological function and stemness of stem cells, leading to improved soft tissue repair and healing by activating the host microenvironment and autologous stem cells.

In this study, a novel electrospun dressing patch made with radially oriented PHBV nanofibers and loaded with berberine was shown to significantly accelerate diabetic wound healing in mice, achieving 100% wound closure in 18 days while also demonstrating improved mechanical and anti-inflammatory properties.

This study reported that a newly developed hydrogel composed of recombinant type I collagen and chitosan, incorporating a metal–polyphenol structure, demonstrated strong mechanical and healing properties, effectively promoting wound healing in a full-thickness skin defect model.

SeV-Tp speeds up healing of drug-resistant infections by targeting wounds and killing bacteria with light activation.

This case report from the University of Alabama, Birmingham describes a rare paradoxical reaction of increased agitation and hyperactivity in a patient with schizoaffective disorder treated with divalproex sodium.

In this study, the researchers developed a hydrogel mimicking the fetal environment that significantly accelerated wound healing and hair follicle regeneration in vivo, with over 94% wound closure in 14 days, surpassing hydrogels lacking certain additives.

This study reported the development of a pH-responsive microreactor that effectively targets infections by eradicating over 99.9% of MRSA and reprogramming the immune response to promote healing, achieving complete infection clearance and tissue regeneration in a 7-day period.

This review discusses recent progress in PENG-based sensors for non-invasive medical diagnosis and treatment but reports no new experimental results.

In this study, researchers used iron ion coordination to successfully create a molecular knot with three organic ligand strands and eight crossings.

In this study, zinc oxide nanoparticles combined with Carbomer940 hydrogel significantly accelerated wound healing and hair growth in Balb/c mice, showing a 56.9% increase in wound closure rate compared to MEBO ointment and control groups, without causing damage or infection.

This study found that combining microneedling with 5% minoxidil improved hair growth in Chinese men with androgenetic alopecia, possibly through activating the Wnt/β-catenin signaling pathway.