A Study of Scarless Wound Healing Through Programmed Inflammation, Proliferation, and Maturation Using a Redox Balancing Nanogel

March 2024 in “ Journal of Biomedical Materials Research Part A ”

Monojit Das, Susmita Mondal, Ria Ghosh, Soumendra Darbar, Lopamudra Roy, Anjan Kumar Das, Debasish Pal, Siddhartha Bhattacharya, Asim Kumar Mallick, Jayanta Kumar Kundu, Samir Kumar Pal

redox balancing nanogel chitosan nanogel citrate capped Mn3O4 nanoparticles reactive oxygen species ROS IL-12 IFN-γ α-SMA angiogenesis

Studysummary In this study on a preclinical mice model, the researchers reported that a chitosan nanogel with Mn₃O₄ nanoparticles facilitated scarless wound healing by regulating reactive oxygen species and influencing signaling molecules throughout the healing stages.

Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer

View this study on onlinelibrary.wiley.com →

Discuss this study in the Community →

Research cited in this study

2 / 2 results

research Wound Healing: Cellular Mechanisms and Pathological Outcomes

1425 citations , September 2020 in “Open Biology”

This review explores the cellular mechanisms of tissue repair and discusses how advancements in understanding wound pathology could lead to the development of more effective therapies for chronic, non-healing wounds, which are prevalent among individuals with diabetes and aging.

research Advances in Skin Grafting and Treatment of Cutaneous Wounds

518 citations , November 2014 in “Science”

This review discusses current and experimental treatments for cutaneous wounds, emphasizing cell-based therapies and skin transplantation, but reports no new clinical results.