Electrospun Scaffold of Collagen and Polycaprolactone Containing ZnO Quantum Dots for Skin Wound Regeneration

The document discusses a study on a new type of wound dressing made from a scaffold of collagen and polycaprolactone, infused with ZnO quantum dots. The scaffold was created using electrospinning, a technique that produces ultra-fine fibers. The study found that the scaffold promoted cell proliferation and migration, crucial for wound healing, and exhibited antibacterial properties. The scaffold also showed good hydrophilicity, high tensile strength, and good biodegradability. In vivo tests on mice showed that the scaffold significantly promoted wound healing, especially when it contained vascular endothelial growth factor (VEGF). The results suggest that this scaffold could be a promising tool for skin wound regeneration.