111 citations,
March 2012 in “Expert Opinion on Drug Delivery” Liposomes could improve how skin care products work but are costly and not very stable.
18 citations,
March 2014 in “Drug Development and Industrial Pharmacy” New gel formulas without ethanol and propylene glycol, containing a minoxidil-methyl-β-cyclodextrin complex, have been created for treating hair loss.
19 citations,
November 2017 in “Journal of Pharmaceutical Sciences” A new gel containing minoxidil can treat hair loss effectively, potentially reducing side effects and improving treatment.
62 citations,
December 2013 in “Aaps Journal” Squarticles effectively deliver hair growth drugs to follicles and dermal papilla cells.
28 citations,
December 2016 in “Journal of Biomedical Materials Research Part A” Bone-forming cells grow well in 3D polymer scaffolds with 35 µm pores.
29 citations,
May 2020 in “npj Regenerative Medicine” Immune cells help regulate hair growth, and better understanding this can improve hair loss treatments.
32 citations,
June 2017 in “Journal of Pharmaceutical Sciences” Chitosan-coated nanoparticles improve skin delivery of hair loss treatments with fewer side effects.
4 citations,
September 2020 in “Frontiers in Microbiology” Algal oligosaccharides help prevent hair loss and promote hair growth.
211 citations,
February 2009 in “European journal of pharmaceutics and biopharmaceutics” Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.
24 citations,
October 2019 in “Biomaterials Research” Minoxidil in HA-PLGA nanoparticles effectively treats alopecia through skin delivery.
48 citations,
May 2008 in “Drug Discovery Today: Disease Mechanisms” Hair follicles offer promising targets for delivering drugs to treat hair and skin conditions.
January 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” A specific enzyme is essential for proper hair follicle stem cell development and healthy skin.
8 citations,
June 2022 in “Cosmetics” Coffee berry extract may help slow skin aging and prevent hair loss.
9 citations,
March 2023 in “Biomimetics” New materials that better mimic natural skin structure could improve healing, especially for chronic wounds.
488 citations,
July 2021 in “Cell” Fibroblasts are crucial for tissue repair and inflammation, and understanding them can help treat fibrotic diseases.
1 citations,
August 2023 in “Advanced Drug Delivery Reviews” Microneedles are promising for long-acting drug delivery and can improve patient compliance, but more data is needed to confirm their effectiveness.
7 citations,
October 2017 in “Artificial Cells Nanomedicine and Biotechnology” Finasteride-loaded ethosomes improve hair loss treatment by targeting pilosebaceous unit.
38 citations,
June 2018 in “Archives of Toxicology” Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.
25 citations,
June 2011 in “International journal of pharmaceutics” Nanoparticles effectively deliver water-insoluble drugs to hair follicles, stimulating hair growth without irritating the skin.
16 citations,
August 2014 in “Archives of Pharmacal Research” Special nanoparticles increased skin absorption of hair loss treatments with fewer side effects.
88 citations,
December 2018 in “Advanced Healthcare Materials” Layer-by-Layer self-assembly is promising for biomedical uses like tissue engineering and cell therapy, but challenges remain in material safety and process optimization.
56 citations,
January 2007 in “Pharmaceutical Development and Technology” Liposomes improve finasteride delivery for hair loss treatment, making it a promising option for topical use.
55 citations,
April 2018 in “Advanced Healthcare Materials” Hydrogels could lead to better treatments for wound healing without scars.
47 citations,
April 2017 in “European Journal of Pharmaceutics and Biopharmaceutics” The new dutasteride formula can be applied to the skin, may promote hair growth, and has fewer side effects.
40 citations,
November 2017 in “International journal of nanomedicine” DA liposomes with chloramphenicol effectively target hair follicles and combat MRSA with minimal skin toxicity.
30 citations,
April 2017 in “Journal of structural biology” Human hair keratin fibers have a detailed nano-scale structure that changes with different conditions.
18 citations,
August 2019 in “Drug Development and Industrial Pharmacy” Quercetin-loaded nanoparticles can penetrate skin, minimize hair loss, and promote hair regrowth, showing slightly better results than a marketed product.
5 citations,
January 2017 in “Journal of Nanomedicine & Nanotechnology” Nanoemulgel could be a promising new treatment for hair loss.
October 2024 in “International Journal of Pharmaceutical Sciences Review and Research” A 5% minoxidil spray could effectively treat male baldness with fewer side effects and better patient comfort.
The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.