Lidocaine-Loaded Solid Lipid Microparticles Produced from Gas-Saturated Solutions for Wound Applications

September 2020 in “ Pharmaceutics ”

Clara López‐Iglesias, Cristina Quílez, Joana Barros, Diego Velasco, Carmen Alvarez‐Lorenzo, José L. Jorcano, Fernando J. Monteiro, Carlos A. García‐González

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lidocaine solid lipid microparticles SLMPs glyceryl monostearate supercritical CO2 3D-bioprinted human skin substitutes

Studysummary In this study, solid lipid microparticles loaded with lidocaine hydrochloride were developed to effectively deliver pain relief and antimicrobial benefits for wound management, demonstrated by testing with bioengineered skin substitutes and showing effectiveness against common wound-infecting bacteria.

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