10 citations
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September 2021 in “International Journal of Nanomedicine” This review explores the potential diagnostic and therapeutic applications of extracellular vesicles in treating various skin conditions but reports no new clinical study results.
4 citations
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March 2022 in “Pharmaceutics” This review explores regenerative treatment options for non-scarring alopecia, with a focus on the potential of mesenchymal stem cells for hair regrowth, but it reports no new clinical results.
2 citations
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February 2024 in “Toxins” This study found that bee venom accelerated the transition from the telogen to anagen phase in mice, increasing hair growth by day 14, and suggested that bee venom may enhance adipose-derived stem cell activity by upregulating growth factor secretion.
2 citations
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June 2022 in “Cells” The study found that growing dermal papilla cells in 3D spheroids enhances their activity with hair growth-promoting agents, such as minoxidil and TCQA, compared to traditional 2D cultures.
2 citations
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September 2017 in “Biotechniques/BioTechniques” This study developed a stable cell line model to evaluate hair differentiation activity, offering a new tool for screening drugs that promote hair growth using mouse iPS cell-derived systems.
1 citations
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July 2025 in “Journal of Photochemistry and Photobiology B Biology” Photobiomodulation helps protect hair follicle cells from damage caused by DHT.
1 citations
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July 2022 in “British Journal of Dermatology” In this study, researchers identified key transcriptome changes in male androgenetic alopecia hair follicles, suggesting that HIF-1 pathway genes and Wnt pathway inhibitors could be potential therapeutic targets.
February 2026 in “International Journal of Molecular Sciences” This study found that PDLLA filler treatment may help combat age-related hair thinning by reducing oxidative stress and enhancing hair follicle function in both cell and animal models.
February 2026 in “Stem Cell Research & Therapy” This review article discusses recent advances in stem cell-based therapies for Alopecia Areata, noting preliminary clinical trials show significant hair regrowth, but emphasizes the need for thorough evaluation of long-term safety and efficacy.
January 2026 in “Dermatologic Therapy” In this review, BTXA treatment was reported to effectively increase hair density and improve follicle health in androgenetic alopecia patients by enhancing scalp blood flow and reducing inflammation, without significant adverse effects.
September 2025 in “Current Issues in Molecular Biology” This study highlights IGF-1's role in promoting hair follicle proliferation, vascularization, and growth, suggesting its potential as a treatment target for hair loss disorders like androgenetic alopecia, though more research on delivery methods and long-term effects is needed.
August 2025 in “Animal nutrition” This study found that supplementing with 1.5% α-ketoglutaric acid significantly improved the performance, hair follicle density, and antioxidant capacity in Rex rabbits, potentially by enhancing the Wnt signaling pathway and reducing amino acid catabolism.
May 2025 in “Lasers in Medical Science” In this study, both erbium: YAG and erbium: glass lasers were found to be effective in treating androgenetic alopecia by improving hair density, growth rate, and thickness, particularly when combined with other therapies like minoxidil or platelet-rich plasma, though individual patient responses varied.
April 2025 in “Journal of Investigative Dermatology” This study found that elevated luteinizing hormone levels were significantly associated with female pattern hair loss, and implicated LH/LHR signaling in the aging and damage of hair follicles.
March 2025 in “International Journal of Molecular Sciences” Veratric Acid may help promote hair growth and reduce hair loss.
December 2024 in “Tissue and Cell” In this study, researchers developed a method to automatically detect androgen receptor nuclear translocation in dermal papilla cells using fluorescence markers and image analysis, finding that the receptor's nuclear signal peaks about 20 minutes after DHT exposure.
August 2024 in “Current Issues in Molecular Biology” In this study, researchers analyzed skin tissue from two sheep breeds during the growing period and identified 56 differentially expressed lncRNAs and 616 mRNAs linked to hair follicle development, suggesting potential targets for improving sheep wool quality through genetic and molecular approaches.
May 2024 in “Journal of cosmetic dermatology” This study found that early-onset male androgenetic alopecia is associated with abnormal lipid metabolism and lower levels of certain serum markers, which may serve as risk factors or protective factors for the condition.
April 2024 in “Clinical, cosmetic and investigational dermatology” This study found that salvianolic acid B significantly enhanced hair growth and delayed hair follicle cycle progression in mice and human hair models, suggesting potential as a treatment for hair loss.
July 2023 in “Journal of Cutaneous and Aesthetic Surgery” This review suggests that combining PRP with minoxidil may be more effective for promoting hair growth in androgenetic alopecia than using either treatment alone, although study variations limit definitive conclusions.
June 2023 in “Antioxidants” This study found that lipids extracted from Schizochytrium sp. significantly enhanced the proliferation and survival of dermal papilla cells under oxidative stress, reduced reactive oxygen species, inhibited ferroptosis, and promoted antioxidant genes, which improved hair growth in experimental settings, suggesting a potential treatment for alopecia.
January 2023 in “Biomedicine & Pharmacotherapy” This study found that human embryonic stem cell-derived mesenchymal stem cells promote hair growth and enhance the transition from the telogen phase to the anagen phase in mice, especially under hypoxic conditions.
November 2022 in “Scientific Data” This study identified downstream genes regulated by androgen receptor signaling in dermal papilla cells and suggests potential molecular targets for treating androgenetic alopecia and prostate cancer.
This study found that platelet-rich plasma significantly enhanced the viability, as well as the expression of alkaline phosphatase and versican, in human hair dermal papilla cells compared to controls.
11 citations
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October 2021 in “Frontiers in Cell and Developmental Biology” This review summarizes the role of non-coding RNAs in hair follicle regeneration and highlights potential therapeutic strategies, though it reports no new experimental results.
3 citations
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May 2022 in “Experimental Dermatology” This review discusses the role of hair follicle stem cell metabolism, ageing, and microenvironment in hair growth disorders and compiles recent research on using stem cell-based regenerative medicine for treating alopecia, without reporting new clinical results.
1 citations
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July 2024 in “International Journal of Molecular Sciences” In this study, miR-181a was found to inhibit the proliferation and induction abilities of ovine dermal papilla cells by targeting the GNAI2 gene and affecting the Wnt/β-Catenin signaling pathway, highlighting its role in the regulation of hair follicle growth and development.
June 2023 in “Stem cell reviews and reports” This review summarizes current methods, effectiveness, and clinical progress of stem cell therapies for androgenetic alopecia, highlighting their potential for hair regrowth and follicle repair despite unclear long-term effects and mechanisms.
This study found significant differences in mRNA and miRNA expression between yak dermal papilla cells and epidermal hair matrix cells, suggesting important roles for these molecules in hair follicle development.
182 citations
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November 2018 in “Cosmetics” This article reviews the empirical use of algae in traditional remedies and highlights the need for scientific understanding of algae's bioactive compounds used in cosmetics without providing new experimental results.