Poly-D,L-Lactic Acid Filler Restores Hair Thickness and Shine by Ameliorating Age-Associated Follicular Decline

    Seyeon Oh, Hosung Choi, Junsu Kim … Kyunghee Byun
    Studysummary This study found that PDLLA filler treatment may help combat age-related hair thinning by reducing oxidative stress and enhancing hair follicle function in both cell and animal models.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on mdpi.com →
    Discuss this study in the Community →

    Research cited in this study 25

    1. A Multifaceted View On Aging Of The Hair And Scalp Cosmetics · 2025
    2. Insulin-Like Growth Factor 1 (IGF-1) in Hair Regeneration: Mechanistic Pathways and Therapeutic Potential Current Issues in Molecular Biology · 2025
    3. Dermal Papilla Cells: From Basic Research to Translational Applications Biology · 2024
    4. Cysteine and Glutamine Levels in Hair Shaft Fracture Patients International Journal of Dermatology Venereology and Leprosy Sciences · 2024
    5. Studying Hair Growth Cycle and Its Effects on Mouse Skin Journal of Investigative Dermatology · 2023
    6. Bioinspired Peptides Designed for Hair Perming and Dyeing With Potential for Repair Acta Biomaterialia · 2023
    7. Enzymatic Crosslinking of Amino Acids Improves the Repair Effect of Keratin on Hair Fiber Polymers · 2023
    8. Age-Associated Thin Hair Displays Molecular, Structural, and Mechanical Characteristic Changes Journal of structural biology · 2022
    9. The Emergent Power of Human Cellular vs Mouse Models in Translational Hair Research Stem Cells Translational Medicine · 2022
    10. De Novo Filament Formation by Human Hair Keratins K85 and K35 Follows a Filament Development Pattern Distinct from Cytokeratin Filament Networks FEBS open bio · 2021
    11. Induction of Hair Keratins Expression by an Annurca Apple-Based Nutraceutical Formulation in Human Follicular Cells Nutrients · 2019
    12. Degradation of Hair Surface: Importance of 18-MEA and Epicuticle Cosmetics · 2019
    13. Types I and II Keratin Intermediate Filaments Cold Spring Harbor Perspectives in Biology · 2018
    14. Beyond Acne: Current Aspects of Sebaceous Gland Biology and Function Reviews in Endocrine and Metabolic Disorders · 2016
    15. Twelve-Point Scale Grading System of Scanning Electron Microscopic Examination to Investigate Subtle Changes in Damaged Hair Surface Skin research and technology · 2016
    16. The Impact of Oxidative Stress on Hair International Journal of Cosmetic Science · 2015
    17. Oxidative Stress-Associated Senescence in Dermal Papilla Cells of Men with Androgenetic Alopecia Journal of Investigative Dermatology · 2015
    18. What Women Want: Quantifying the Perception of Hair Amount - An Analysis of Hair Diameter and Density Changes with Age in Caucasian Women British Journal of Dermatology · 2012
    19. Morphological, Macromolecular Structure and Hair Growth 2011
    20. Hair Cuticle Differences Between Asian And Caucasian Females International Journal of Dermatology · 2006
    21. K25 (K25irs1), K26 (K25irs2), K27 (K25irs3), And K28 (K25irs4) Represent The Type I Inner Root Sheath Keratins Of The Human Hair Follicle Journal of Investigative Dermatology · 2006
    22. The Expression of Insulin-Like Growth Factor 1 in Follicular Dermal Papillae Correlates with Therapeutic Efficacy of Finasteride in Androgenetic Alopecia Journal of The American Academy of Dermatology · 2003
    23. Control of Hair Growth and Follicle Size by VEGF-Mediated Angiogenesis Journal of Clinical Investigation · 2001
    24. Hair Density, Hair Diameter, and the Prevalence of Female Pattern Hair Loss British Journal of Dermatology · 2001
    25. The Biology of Hair Follicles The New England Journal of Medicine · 1999