Morphological, Macromolecular Structure and Hair Growth

The cell membrane complex in mammalian hair has three distinct types with different structures and chemical properties.

Human beard hair medulla contains a unique and complex mix of keratins not found in other human tissues.

Chinese men have lower AGA rates than Caucasians, with type III vertex most common; family history is important.

Hair curvature in Japanese people is linked to specific cell types and filament arrangements in the hair cortex.

Japanese women's curved hair has an uneven internal structure and varying amino acid composition.

Curly hair shape is due to uneven growth patterns in the hair follicle.

Oxidation changes the structure of hair protein filaments, causing them to compact and rearrange.

Japanese women typically start experiencing hair loss after 40, with reduced hair density and thickness being the main factors.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Hair curliness is due to uneven distribution of different cortices within the hair fiber.

The document concludes that the hair cycle is a complex process involving growth, regression, and rest phases, regulated by various molecular signals.

The document concludes that hair transplantation is recommended for those not helped by medical treatments, but warns that high-density transplants may lower hair survival rates.

Different ethnic groups have unique hair growth patterns, with African hair growing slower and less dense, Asian hair growing fast but sparse, and Caucasian hair being densest; men are more likely to experience hair loss than women.

Sgk3 is essential for normal hair follicle growth and maintenance.

Hair breaks differently when wet or dry and is affected by its condition and treatments like perms and bleaching.

Hard α-keratin in hair has a unique, nonordered structure, different from other fibers.

Temporary activation of β-catenin can create new hair follicles, but ongoing activation is needed to keep hair follicle tumors.

Hair follicle growth and development are controlled by specific genes and molecular signals.

Hair growth and shedding are linked and can be disrupted, causing a delay known as the hair eclipse phenomenon, which is common in certain hair conditions and could lead to new treatments.

Gene therapy shows promise for treating hair loss by targeting hair follicles.

Pregnant women's hair gets thicker.

Msx2-deficient mice experience irregular hair growth and loss due to disrupted hair cycle phases.

Understanding hair follicle development can help treat hair loss, skin regeneration, and certain skin cancers.

Human hair keratins were cataloged, showing their roles in hair differentiation stages.

AGA more common in men, Koreans have lower rates and unique patterns.

A cluster of sulfur-rich hair protein genes was found on chromosome 17.

FPHL affects hair density and diameter, causing visible hair loss in older women.

Adult mouse skin contains stem cells that can create new hair, skin, and oil glands.

Hair loss in women is common, starts in late 20s, and affects 30% of women over 50.

Inhibiting Bmp signaling disrupts hair growth and differentiation.

Notch pathway activation causes abnormal hair layer development.

Activated LEF/TCF complexes are crucial for hair development and cycling.

Hair follicle biology advancements may lead to better hair growth disorder treatments.

Human hair is made up of different keratins, some strong and some weak, with specific types appearing at various stages of hair growth.

African Americans have less hair density than whites.

A mutation in the human hairless gene causes alopecia universalis.

Keratin proteins and their genes are crucial for hair growth and structure.

Human hair growth and structure are influenced by keratin proteins, genes, melanin, and lipids.

Finasteride increases hair growth, prolongs hair cycle, and lowers dihydrotestosterone levels.

Finasteride reduces scalp DHT levels, potentially treating male pattern baldness.

EGF makes hair follicles grow longer but stops hair production.

Mature hair surfaces are formed by keratinized cells with developed layers, not just modified plasma membranes.

Horizontal scalp biopsy sections effectively diagnose and predict MPAA, with follicular density and inflammation impacting hair regrowth.

KAP6 genes are conserved across species and active in hair follicles.

Diffuse alopecia in women may be related to androgens and iron deficiency, and basic hormone and nutrient screening is useful.

Men with male-pattern baldness have more androgen receptors in their scalp's oil glands, which may contribute to hair loss.

Hair follicle shape determines hair type: curly, straight, or in-between.

The document concludes that treatments for female hair loss and excessive hair growth are temporary and not well-studied.

Different animals have unique versions of the enzyme that changes testosterone into another hormone, which is important for creating effective treatments for prostate and hair loss conditions.

Moisture content significantly affects how human hair breaks.

Common baldness, also known as Androgenetic Alopecia, is caused by a combination of genetic factors and hormones called androgens.

Papain and bisulfite break down human hair by dissolving parts of it.

A fatty acid/protein complex in human hair helps protect it from damage.

Hair and wool have complex microscopic structures with microfibrils and varying cystine content.