The Use of Botulinum Toxin in the Treatment of Androgenetic Alopecia: A Systematic Review

    January 2026 in “ Dermatologic Therapy
    Anna Zygmunt, Anna Mandecka, Łukasz Mikołaj Karoń … Beata Bergler-Czop
    Studysummary In this review, BTXA treatment was reported to effectively increase hair density and improve follicle health in androgenetic alopecia patients by enhancing scalp blood flow and reducing inflammation, without significant adverse effects.
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    Research cited in this study 24

    1. A Review on Androgenic Alopecia: Etiology, Pathogenesis, Pharmacological and Non-Pharmacological Treatment Approaches Ain Shams Medical Journal · 2024
    2. Assessing the Efficacy and Quality of Life Improvements of Botulinum Toxin Type A with Topical Minoxidil Versus Topical Minoxidil in Male Androgenetic Alopecia: A Randomized Controlled Trial Archives of Dermatological Research · 2024
    3. Efficacy of Botulinum Toxin in Male Androgenetic Alopecia: A Triple-Blind, Randomized Clinical Trial Journal of the American Academy of Dermatology · 2024
    4. Efficacy of Type A Botulinum Toxin Treatment for Androgenetic Alopecia Using Ultrasound Combined with Trichoscopy Skin Research and Technology · 2024
    5. Intradermal Injection in Balding Region Versus Intramuscular Injection in Surrounding Muscles: A Split-Scalp, Randomized Trial on Botulinum Toxin for Androgenetic Alopecia Dermatology and therapy · 2024
    6. Efficacy and Safety of Botulinum Toxin A in the Treatment of Female Pattern Hair Loss Skin research and technology · 2024
    7. Hair-To-Hair Trichoscopy: An Objective Method To Assess Effectiveness Of Botulinum Toxin In A Clinical Trial For Androgenetic Alopecia Skin appendage disorders · 2023
    8. Assessment of Efficacy of Different Botulinum Toxin A Concentrations in the Treatment of Androgenetic Alopecia Assessed by Dermoscopy Journal of Cosmetic Dermatology · 2023
    9. New Target for Minoxidil in the Treatment of Androgenetic Alopecia Drug Design Development and Therapy · 2023
    10. Androgenetic Alopecia: Therapy Update Drugs · 2023
    11. Pathogenesis of Androgenetic Alopecia 2022
    12. A Study of Combination Unilateral Subcutaneous Botulinum Toxin A Treatment for Androgenetic Alopecia Journal of Cosmetic Dermatology · 2022
    13. Skin, Hair, and Beyond: The Impact of Menopause Climacteric · 2022
    14. The Effect of Intradermal Botulinum Toxin on Androgenetic Alopecia and Its Possible Mechanism Journal of The American Academy of Dermatology · 2020
    15. Effectiveness and Safety of Botulinum Toxin Type A in the Treatment of Androgenetic Alopecia BioMed Research International · 2020
    16. A Small Dose of Botulinum Toxin A Is Effective for Treating Androgenetic Alopecia in Chinese Patients Dermatologic Therapy · 2018
    17. Androgenetic Alopecia: Diagnostic and Therapeutic Recommendations of the Polish Dermatological Society Dermatology Review/Przegląd Dermatologiczny · 2018
    18. Involvement of Mechanical Stress in Androgenetic Alopecia International Journal of Trichology · 2015
    19. Evidence of Increased DNA Methylation of the Androgen Receptor Gene in Occipital Hair Follicles from Men with Androgenetic Alopecia British Journal of Dermatology · 2011
    20. Treatment of Male Pattern Baldness with Botulinum Toxin: A Pilot Study Plastic and Reconstructive Surgery · 2010
    21. Effect of 5α-Dihydrotestosterone and Testosterone on Apoptosis in Human Dermal Papilla Cells Skin Pharmacology and Physiology · 2006
    22. Identification of Androgen-Inducible TGF-β1 Derived from Dermal Papilla Cells as a Key Mediator in Androgenetic Alopecia Journal of Investigative Dermatology Symposium Proceedings · 2003
    23. Androgenetic Alopecia: Pathogenesis and Potential for Therapy Expert Reviews in Molecular Medicine · 2002
    24. Androgen-Inducible TGF-β1 from Balding Dermal Papilla Cells Inhibits Epithelial Cell Growth: A Clue to Understanding Paradoxical Effects of Androgen on Human Hair Growth ˜The œFASEB journal · 2002