Involvement of Mechanical Stress in Androgenetic Alopecia

    January 2015 in “ International Journal of Trichology ”
    Rafael Tellez-Segura
    Studysummary This study suggests that mechanical stress may influence androgenic alopecia patterning through a stretch-induced and androgen-mediated mechanotransduction mechanism in dermal papilla cells.
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    Research cited in this study 15

    1. Androgen Receptor Transactivity Is Potentiated by TGF-β1 Through Smad3 but Checked by Its Coactivator Hic-5/ARA55 in Balding Dermal Papilla Cells Journal of Dermatological Science · 2011
    2. Molecular Basis of Androgenetic Alopecia: From Androgen to Paracrine Mediators Through Dermal Papilla Journal of Dermatological Science · 2010
    3. Treatment of Male Pattern Baldness with Botulinum Toxin: A Pilot Study Plastic and Reconstructive Surgery · 2010
    4. Female Pattern Hair Loss in Complete Androgen Insensitivity Syndrome British Journal of Dermatology · 2010
    5. Androgenetic Alopecia in Males: A Histopathological and Ultrastructural Study Journal of Cosmetic Dermatology · 2009
    6. Male Androgenetic Alopecia: Population-Based Study in 1,005 Subjects International Journal of Trichology · 2009
    7. Baldness, Benign Prostate Hyperplasia, Prostate Cancer, and Androgen Levels The Aging Male · 2008
    8. Perifollicular Fibrosis: Pathogenetic Role in Androgenetic Alopecia Biological & Pharmaceutical Bulletin · 2006
    9. Patients With a Large Prostate Show a Higher Prevalence of Androgenetic Alopecia Archives of Dermatological Research · 2004
    10. Minoxidil: Mechanisms of Action on Hair Growth British Journal of Dermatology · 2004
    11. Identification of Androgen-Inducible TGF-β1 Derived from Dermal Papilla Cells as a Key Mediator in Androgenetic Alopecia Journal of Investigative Dermatology Symposium Proceedings · 2003
    12. Androgen-Inducible TGF-β1 from Balding Dermal Papilla Cells Inhibits Epithelial Cell Growth: A Clue to Understanding Paradoxical Effects of Androgen on Human Hair Growth ˜The œFASEB journal · 2002
    13. Surgical Anatomy of the Scalp Dermatologic Surgery · 2002
    14. Androgenetic Alopecia and Microinflammation International Journal of Dermatology · 2000
    15. Immunohistochemical Analysis of Tissue Remodeling During the Anagen-Catagen Transition of the Human Hair Follicle British Journal of Dermatology · 1997

    Related research 9

    1. Molecular Basis of Androgenetic Alopecia: From Androgen to Paracrine Mediators Through Dermal Papilla Journal of Dermatological Science · 2010
    2. Relation Between Dermal Papilla Cells and Androgenetic Alopecia International Journal of Dermatology and Venereology · 2010
    3. Hair Follicle Neogenesis Induced by Cultured Human Scalp Dermal Papilla Cells Regenerative Medicine · 2009
    4. Male Androgenetic Alopecia The Journal of Men's Health & Gender · 2004
    5. The Hair Follicle: A Paradoxical Androgen Target Organ Hormone Research in Paediatrics · 2000
    6. Differences in Hair Follicle Dermal Papilla Volume Are Due to Extracellular Matrix Volume and Cell Number: Implications for the Control of Hair Follicle Size and Androgen Responses Journal of Investigative Dermatology · 1999
    7. Balding Hair Follicle Dermal Papilla Cells Contain Higher Levels of Androgen Receptors Than Those From Non-Balding Scalp Journal of Endocrinology · 1998
    8. Original Study: Comparison of Androgen Receptor Expression in Lesional and Non-Lesional Areas of Androgenetic Alopecia 대한피부과학회지 · 1994
    9. Hormones and Hair Growth: Variations in Androgen Receptor Content of Dermal Papilla Cells Cultured from Human and Red Deer Hair Follicles ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1993