MicroRNA-181a Targets GNAI2 and Affects the Proliferation and Induction Ability of Dermal Papilla Cells: Potential Involvement of the Wnt/β-Catenin Signaling Pathway

    July 2024 in “ International Journal of Molecular Sciences ”
    Mingliang He, Xiaoyang Lv, Joram M. Mwacharo … Wei Sun
    Studysummary In this study, miR-181a was found to inhibit the proliferation and induction abilities of ovine dermal papilla cells by targeting the <i>GNAI2</i> gene and affecting the Wnt/β-Catenin signaling pathway, highlighting its role in the regulation of hair follicle growth and development.
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    Research cited in this study 18

    1. MiR-23b and miR-133 Co-Target TGFβ2/NOTCH1 in Sheep Dermal Fibroblasts, Affecting Hair Follicle Development Cells · 2024
    2. Sox18 Promotes the Proliferation of Dermal Papilla Cells via the Wnt/β-Catenin Signaling Pathway International Journal of Molecular Sciences · 2023
    3. MiR-23b and MiR-133 Cotarget TGFβ2/NOTCH1 in Dermal Fibroblasts and Affect Hair Follicle Development in Sheep Research Square (Research Square) · 2023
    4. Regulation of Secondary Hair Follicle Cycle in Cashmere Goats by miR-877-3p Targeting IGFBP5 Gene Journal of Animal Science · 2023
    5. Exosomal miRNA-181a-5p from Hair Follicle Dermal Papilla Cells Promotes Hair Follicle Growth and Development via the Wnt/β-Catenin Signaling Pathway International journal of biological macromolecules · 2022
    6. KY19382, A Novel Activator of Wnt/β-Catenin Signalling, Promotes Hair Regrowth and Hair Follicle Neogenesis British Journal of Pharmacology · 2021
    7. Twist1 Contributes to the Maintenance of Some Biological Properties of Dermal Papilla Cells In Vitro by Forming a Complex With Tcf4 and β-Catenin Frontiers in Cell and Developmental Biology · 2020
    8. Dermal Exosomes Containing miR-218-5p Promote Hair Regeneration by Regulating β-Catenin Signaling Science Advances · 2020
    9. Preliminary Study on MicroR-148a and MicroR-10a in Dermal Papilla Cells of Hu Sheep BMC Genetics · 2019
    10. The Mesenchymal Niche of the Hair Follicle Induces Regeneration by Releasing Primed Progenitors from Inhibitory Effects of Quiescent Stem Cells Cell Reports · 2018
    11. miR-195-5p Regulates Hair Follicle Inductivity of Dermal Papilla Cells by Suppressing Wnt/β-Catenin Activation BioMed Research International · 2018
    12. Epithelial-Mesenchymal Micro-Niches Govern Stem Cell Lineage Choices Cell · 2017
    13. Hair Curvature: A Natural Dialectic and Review Biological reviews/Biological reviews of the Cambridge Philosophical Society · 2014
    14. Dermal Papilla Cell Number Specifies Hair Size, Shape, and Cycling, and Its Reduction Causes Follicular Decline Development · 2013
    15. Live Imaging of Stem Cell and Progeny Behavior in Physiological Hair-Follicle Regeneration Nature · 2012
    16. Micro-RNA-31 Controls Hair Cycle-Associated Changes in Gene Expression Programs of the Skin and Hair Follicle ˜The œFASEB journal · 2010
    17. Biology of the Wool Follicle: An Excursion into a Unique Tissue Interaction System Waiting to Be Rediscovered Experimental Dermatology · 2006
    18. Hair Follicle Pigmentation: Mechanisms and Factors Influencing Melanin Production ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2005

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