1 citations
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July 2024 in “International Journal of Molecular Sciences” In this study, miR-181a was found to inhibit the proliferation and induction abilities of ovine dermal papilla cells by targeting the GNAI2 gene and affecting the Wnt/β-Catenin signaling pathway, highlighting its role in the regulation of hair follicle growth and development.
18 citations
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July 2014 in “Molecular Medicine Reports” This study found that UVB radiation significantly alters miRNA expression and induces cytotoxicity and apoptosis in normal human dermal papilla cells.
12 citations
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May 2015 in “Molecular Medicine Reports” This study demonstrated that troxerutin may protect human dermal papilla cells from H2O2-induced damage and suggests potential in treating alopecia by inhibiting ROS-mediated cellular damage.
25 citations
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March 2022 in “International journal of biological macromolecules” This study found that exosomal miR-181a-5p promotes hair follicle growth and development in vitro by activating the Wnt/β-catenin signaling pathway and suppressing hair follicle stem cell apoptosis.
August 2026 in “Aesthetic Plastic Surgery” In this study, hair follicle stem cell-derived exosomes enriched with miR-181a-5p accelerated hair regrowth and the transition from telogen to anagen in mice, with up to 90% hair coverage observed, suggesting enhanced activation of the Wnt/β-catenin pathway compared to controls.