19 citations
,
October 2020 in “Biomedical Microdevices” This review discusses the use of derma rollers for cosmetic purposes and their potential in transdermal drug delivery by summarizing evidence on their design, efficacy, safety, and concerns from preclinical and clinical reports.
September 2024 in “Journal of Dental Specialities” This study found that platelet-rich plasma combined with micro-needling significantly increased hair density and thickness in patients with androgenetic alopecia, with mild side effects reported, though further high-quality trials are needed to validate these results and standardize treatments.
July 2023 in “International journal of dermatology, venereology and leprosy sciences” This review discusses micro needling as a therapeutic option for various dermatological conditions, such as scars and pigmentation, and reports no new clinical results; the authors note potential side effects and contraindications.
11 citations
,
November 2023 in “Skin Research and Technology” A 2 mm needle is effective and precise for skin injections.
5 citations
,
March 2019 in “Journal of The American Academy of Dermatology” This commentary discusses a study reporting that platelet-rich plasma (PRP) treatment led to increased hair growth in androgenetic alopecia patients, while critiquing its conclusion on the ineffectiveness of microneedling.
April 2019 in “Lincoln (University of Nebraska)” This study engineered a programmable platform using miniaturized needle arrays for drug delivery, showing improved wound healing outcomes in diabetic mice compared to standard topical treatments.
166 citations
,
February 2020 in “Advanced Functional Materials” This study reports that a novel programmable device delivering VEGF through miniaturized needles significantly improved healing outcomes in diabetic mice's chronic wounds compared to traditional topical treatments.
This case report observed that a 44-year-old male patient with androgenetic alopecia experienced increased hair density and patient satisfaction after treatment with microneedling, growth factors, and minoxidil.
January 2023 in “International journal of dermatology, venereology and leprosy sciences” This study suggests that microneedling may be an effective and less painful treatment for vitiligo, offering benefits over traditional needle injections, particularly in challenging-to-treat areas like the extremities or stubborn regions.
November 2023 in “International Journal of Medical Sciences” This review examines the mechanisms of hair follicle development and regeneration, discussing current hair loss treatments and emerging therapies like low-level laser therapy and stem cell therapy, which the authors suggest show promise in managing hair loss.
July 2026 in “Lasers in Medical Science” In this study, the Peninsula Timerevert Needle was found to provide effective treatment for skin photoaging and acne scars with less pain and shorter treatment duration compared to EndyMed, although it caused more bleeding.
19 citations
,
February 2008 in “Archives of Dermatological Research” This study observed that mast cells and increased collagen and elastic fibers in the scalp may contribute to male pattern hair loss, but additional research is needed for further understanding.
August 2025 in “Nutrients” This study found that Ageratum conyzoides extract enhanced hair growth in mice and human follicle cells, showing potential for hormonal modulation, pathway activation, and antioxidant protection; however, further clinical studies are needed to confirm efficacy in humans.
This review reports that collagen as a nutraceutical shows promising results for improving skin health in estrogen-deficient women, but more research is needed for scalp hair, nail health, and optimal dosing of curcumin and glutathione.
February 2025 in “Journal of Investigative Dermatology” DMG-Na may help reduce hair loss and improve hair growth, but more research is needed.
December 2024 in “Globus: an international journal of medical science, engineering and technology.” This study found that 10% Citrus aurantium peel oil significantly promoted hair growth in ICR mice by reducing the time needed for hair growth initiation and completion, and by increasing hair length, follicle diameter, and count, showing potential as a hair growth agent.
1 citations
,
January 2022 in “Pharmaceutical Sciences Asia” This review highlights the potential of microneedles as a low-cost, well-tolerated method for transdermal drug delivery in dermatology, though further research is needed to establish their clinical efficacy.
July 2024 in “Journal of Cosmetic Dermatology” This case study suggests that rose stem cell-derived exosomes, administered via noninvasive electroporation, may promote hair regeneration in androgenetic alopecia; larger studies are needed to confirm these findings.
July 2024 in “Gene & Protein in Disease” This review discusses the potential of exosome-based therapies in dermatology, highlighting their ability to treat conditions like alopecia and accelerate wound healing, though further research is needed to understand long-term safety and develop standardized clinical protocols.
June 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” This pilot study suggests that a new preparation of platelet-rich plasma gel may improve symptoms and tissue regeneration in patients with en coup de sabre scleroderma, though further trials are needed to clarify its role.
January 2019 in “Springer eBooks” PRP may help with hair loss and improve hair quality with few side effects, but more research is needed.
June 2024 in “Annals of the College of Medicine Mosul/Annals of the College of Medecine” This study explored the use of microneedling for dermatological disorders, highlighting its benefits like increased collagen and elastin production, dermal thickening, and skin rejuvenation, making it suitable for conditions such as scars, stretch marks, and photoaged skin.
November 2023 in “Materials Today Bio” This article discusses photobiomodulation as a potential adjunct to hair follicle organoid culture for androgenic alopecia, reporting no new results and suggesting further study is needed.
34 citations
,
July 2018 in “Veterinary Dermatology” This study established a 3D in vitro culture system of canine keratinocyte organoids to study epidermal function and address skin disorders in dogs, though additional growth factors are needed for hair follicle development.
33 citations
,
January 2021 in “Aesthetic Surgery Journal” This review suggested that low-level light therapy using red/near-infrared light could be a safe and effective treatment for various skin and hair conditions, though more robust trials are needed to solidify its clinical utility.
13 citations
,
July 2012 in “Dermatologic Surgery” Platelet-rich plasma (PRP) may help promote hair growth and improve graft survival after hair transplantation, but more research is needed to confirm its effectiveness and determine the best dosage.
13 citations
,
December 2011 in “Korean Journal of Food Science and Technology” This study suggests that black soybean extract promotes hair growth and improves scalp health by enhancing blood circulation and cellular proliferation, although further human studies are needed to verify these effects.
12 citations
,
May 2022 in “Plants” This review highlights the potential of nano-phytopharmaceuticals in improving the bioavailability and efficacy of phytochemicals for treating locomotor, dermal, reproductive, and urinary tract disorders, but notes that more clinical and preclinical research is needed to establish their safety and efficacy for human use.
10 citations
,
August 2024 in “Clinical Cosmetic and Investigational Dermatology” This review reports that natural compounds show promise in slowing skin photoaging by targeting cellular pathways in keratinocytes and fibroblasts. However, comprehensive clinical studies are needed to verify their efficacy and safety.
2 citations
,
January 2022 in “Stem cell biology and regenerative medicine” This review discusses the potential of extracellular vesicles from various sources as promising candidates for hair growth stimulation but notes that clinical trials are needed to confirm their effectiveness and safety.