TLDR The smart bandage improved healing in diabetic mice by delivering drugs directly into wounds.
The study presented a wirelessly controlled smart bandage featuring 3D-printed miniaturized needle arrays designed for the treatment of chronic wounds, particularly in diabetic patients. This innovative platform allowed for the programmable delivery of various drugs directly into the deeper layers of the wound bed, which was crucial for effective healing. The research demonstrated that delivering vascular endothelial growth factor (VEGF) using this method significantly improved wound closure, re-epithelialization, angiogenesis, and hair growth in diabetic mice compared to traditional topical treatments. The findings highlighted the importance of both the choice of therapeutics and the delivery method in enhancing wound healing outcomes.
520 citations
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February 2001 in “Journal of Clinical Investigation” VEGF helps hair grow and determines follicle size by increasing blood vessel growth.
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