A Wirelessly Controlled Smart Bandage with 3D-Printed Miniaturized Needle Arrays

    February 2020 in “ Advanced Functional Materials ”
    Hossein Derakhshandeh, Fariba Aghabaglou, Alec McCarthy, Azadeh Mostafavi, Chris Wiseman, Zack Bonick, Ian Ghanavati, Seth Harris, Craig Kreikemeier‐Bower, Seyed Masoud Moosavi Basri, Jordan Rosenbohm, Ruiguo Yang, Pooria Mostafalu, Dennis P. Orgill, Ali Tamayol
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    Studysummary This study reports that a novel programmable device delivering VEGF through miniaturized needles significantly improved healing outcomes in diabetic mice's chronic wounds compared to traditional topical treatments.
    Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
    The study presented a wirelessly controlled smart bandage featuring 3D-printed miniaturized needle arrays designed for the treatment of chronic wounds, particularly in diabetic patients. This innovative platform allowed for the programmable delivery of various drugs directly into the deeper layers of the wound bed, which was crucial for effective healing. The research demonstrated that delivering vascular endothelial growth factor (VEGF) using this method significantly improved wound closure, re-epithelialization, angiogenesis, and hair growth in diabetic mice compared to traditional topical treatments. The findings highlighted the importance of both the choice of therapeutics and the delivery method in enhancing wound healing outcomes.
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