Hair and Scalp

January 2019 in “ Springer eBooks ”

Margo Gkini, M Goisis, Sara Izzo

platelet-rich plasma androgenetic alopecia growth factors PDGF TGF VEGF IGF adipose-derived stem cells dermal nanofat system PRP AGA ADSCs

TLDR PRP may help with hair loss and improve hair quality with few side effects, but more research is needed.

The document from 2019 discusses the potential of platelet-rich plasma (PRP) as a treatment for androgenetic alopecia (AGA), highlighting its rich content of growth factors such as PDGF, TGF, VEGF, and IGF that can promote hair growth. It outlines the PRP treatment protocol, which includes multiple sessions and a booster, and reports improvements in hair loss, count, diameter, density, volume, and quality, with a low risk of adverse effects. However, it calls for more extensive trials to confirm PRP's efficacy and safety. The document also touches on the positive impact of adipose-derived stem cells (ADSCs) on hair growth and details a dermal nanofat system procedure for hair treatment, including the preparation and injection techniques. It suggests PRP could be used alone in early AGA stages or alongside conventional treatments in advanced cases, and it references studies on PRP, growth factors, and ADSCs in skin and hair treatments.

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Research cited in this study

12 / 12 results

research Clinical Use of Conditioned Media of Adipose Tissue-Derived Stem Cells in Female Pattern Hair Loss: A Retrospective Case Series Study

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research Platelet-Rich Plasma as a Potential Treatment for Noncicatricial Alopecias

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Platelet-rich plasma, which carries growth factors, could be a promising treatment for non-scarring hair loss, promoting hair growth and density with no major side effects.

research Evaluation and Diagnosis of the Hair Loss Patient

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research Evaluation and Diagnosis of the Hair Loss Patient

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research Study of Platelet-Rich Plasma Injections in the Treatment of Androgenetic Alopecia Through a One-Year Period

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research Evidence-Based Guideline for the Treatment of Androgenetic Alopecia in Women and Men

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Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.

research Hair Growth Promoting Effects of Adipose Tissue-Derived Stem Cells

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Fat tissue stem cells may help increase hair growth.

research The Role of Platelet Plasma Growth Factors in Male Pattern Baldness Surgery

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Using platelet plasma growth factors in baldness surgery can increase the number of hair follicles.

research Increased Vibrissa Growth in Transgenic Mice Expressing Insulin-Like Growth Factor 1

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IGF-1 increases whisker growth in transgenic mice.

Growth Factors and Cytokines in Hair Follicle Development and Cycling: Recent Insights from Animal Models and the Potentials for Clinical Therapy

research Growth Factors and Cytokines in Hair Follicle Development and Cycling: Recent Insights from Animal Models and the Potentials for Clinical Therapy

100 citations, November 1996 in “Molecular Medicine Today”

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Hair and Scalp

Research cited in this study

research Clinical Use of Conditioned Media of Adipose Tissue-Derived Stem Cells in Female Pattern Hair Loss: A Retrospective Case Series Study

research Platelet-Rich Plasma as a Potential Treatment for Noncicatricial Alopecias

research Evaluation and Diagnosis of the Hair Loss Patient

research Evaluation and Diagnosis of the Hair Loss Patient

research Platelet-Rich Plasma in Dermatology: Boon or Bane?

research Study of Platelet-Rich Plasma Injections in the Treatment of Androgenetic Alopecia Through a One-Year Period

research Autologous Platelet-Rich Plasma: A Potential Therapeutic Tool for Promoting Hair Growth

research Evidence-Based Guideline for the Treatment of Androgenetic Alopecia in Women and Men

research Hair Growth Promoting Effects of Adipose Tissue-Derived Stem Cells

research The Role of Platelet Plasma Growth Factors in Male Pattern Baldness Surgery

research Increased Vibrissa Growth in Transgenic Mice Expressing Insulin-Like Growth Factor 1

research Growth Factors and Cytokines in Hair Follicle Development and Cycling: Recent Insights from Animal Models and the Potentials for Clinical Therapy

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research Advances in Hair Restoration: Wnt/Beta-Catenin Pathway and Stem Cell-Based Therapies

research Platelet Lysate: A Promising Candidate in Regenerative Medicine

research Advances in Regenerative Stem Cell Therapy in Androgenic Alopecia and Hair Loss: Wnt Pathway, Growth Factor, and Mesenchymal Stem Cell Signaling Impact Analysis on Cell Growth and Hair Follicle Development

research Novel Therapeutic Approaches in Utilizing Platelet Lysate in Regenerative Medicine: Are We Ready for Clinical Use?

research Autologous Platelet-Rich Plasma for the Treatment of Pattern Hair Loss