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This study found that mice with a disrupted TGFα gene display a curly whisker-coat phenotype, similar to waved-1 mice, suggesting TGFα's crucial role in skin architecture and hair development.

This study observed that overexpression of TGF-alpha in transgenic mice led to thicker epidermis and stunted hair growth, particularly in regions with normally thick skin and low hair density.

This study identified TGF-β2 as a crucial signal in hair follicle stem cell regeneration, highlighting its role in counteracting BMP signaling to promote tissue regeneration.

In this study, androgen did not affect keratinocyte growth in coculture with androgenetic alopecia-derived dermal papilla cells, but did significantly suppress keratinocyte growth when androgen receptor was overexpressed in the papilla cells.

This review explores the role of TGF-β superfamily pathways in stem cell environments and their implications for tissue regeneration and cancer development, reporting no new experimental results.