Exosomes And Stem Cells
January 2021
Research cited in this study
28 / 28 results
research The Novel Mechanisms and Applications of Exosomes in Dermatology and Cutaneous Medical Aesthetics
This review discusses the potential of endogenic and exogenous exosomes in dermatology and cutaneous aesthetics, highlighting their capacity to repair and rejuvenate skin tissue, but reports no new experimental results.
research Regenerative Medicine and Hair Loss: To Exosome or Not to Exosome
This article highlights online claims about exosomes as a promising hair loss treatment but reports no clinical results; it calls attention to the need for critical evaluation and further research.
research Comparison of the Therapeutic Effect of Allogeneic and Xenogeneic Small Extracellular Vesicles in Soft Tissue Repair
This study found that both allogeneic and xenogeneic small extracellular vesicles from adipose tissue similarly enhanced soft tissue regeneration and wound healing in rat models, implying similar therapeutic effects across species.
research A Randomized, Double-Blind, Vehicle-Controlled Clinical Study of Hair Regeneration Using Adipose-Derived Stem Cell Constituent Extract in Androgenetic Alopecia
In this randomized clinical trial, the authors reported that adipose-derived stem cell constituent extract topical solution increased hair density and thickness in patients with androgenetic alopecia over 16 weeks compared to placebo.
research Efficacy of Non-Surgical Treatments for Androgenetic Alopecia in Men and Women: A Systematic Review with Network Meta-Analyses and an Assessment of Evidence Quality
This study suggests platelet-rich plasma may be more effective than other non-surgical treatments for male androgenetic alopecia, while low-level laser therapy ranks highest for women; however, the evidence quality was low.
research Hopes and Limits of Adipose-Derived Stem Cells and Mesenchymal Stem Cells in Wound Healing
This paper discusses the potential roles of adipose tissue derived stem cells in skin regeneration and wound healing but emphasizes the need for further research on their effectiveness in clinical settings.
research Sustained Release of Dermal Papilla-Derived Extracellular Vesicles from Injectable Microgel Promotes Hair Growth
This study demonstrated that OSA hydrogels enhanced the stability and retention of dermal papilla-derived extracellular vesicles, which significantly improved hair regeneration in both cultured human hair and a mouse depilation model.
research Sequential Scalp Assessment in Hair Regeneration Therapy Using an Adipose-Derived Stem Cell-Conditioned Medium
This study found that intradermal administration of adipose-derived stem cell–conditioned medium significantly increased hair density and dermal thickness, suggesting potential regenerative effects on both hair follicles and the interfollicular scalp in patients with alopecia.
research A Therapeutic Microneedle Patch Made from Hair-Derived Keratin for Promoting Hair Regrowth
In a mouse model, this study demonstrated that a microneedle patch system using keratin and integrated with MSC-derived exosomes and UK5099 promoted hair regrowth more efficiently than traditional delivery methods.
research Exosomes Derived from Human Dermal Papilla Cells Promote Hair Growth in Cultured Human Hair Follicles and Augment the Hair-Inductive Capacity of Cultured Dermal Papilla Spheres
This study suggests that exosomes derived from dermal papilla cells, especially those cultured in three dimensions, promote hair growth and regeneration by enhancing follicular cell activity.
research Review of Human Hair Follicle Biology: Dynamics of Niches and Stem Cell Regulation for Possible Therapeutic Hair Stimulation for Plastic Surgeons
This review discusses the latest understanding of androgenetic alopecia, including stem cell niches in hair follicles, and highlights emerging treatments like growth factors and platelet-rich plasma without new clinical findings.
research Cellular Therapy with Human Autologous Adipose-Derived Adult Cells of Stromal Vascular Fraction for Alopecia Areata
In this study, patients receiving adipose-derived stromal vascular cell transplantation for alopecia areata experienced significant hair regeneration, increased growth, and improved hair quality after 3 and 6 months, indicating potential efficacy of this stem cell-based therapy for hair loss.
research Regulation of Hair Follicle Development by Exosomes Derived from Dermal Papilla Cells
In this study, dermal papilla cell-derived exosomes accelerated hair follicle growth in mice, suggesting potential for treating hair loss by modulating key signaling pathways.
research Introducing Platelet-Rich Stroma: Platelet-Rich Plasma and Stromal Vascular Fraction Combined for the Treatment of Androgenetic Alopecia
This study found that a single injection of platelet-rich stroma significantly increased hair density in men with androgenetic alopecia within 6 to 12 weeks, with no reported side effects.
research Extracellular Vesicles Derived from MSCs Activate Dermal Papilla Cells In Vitro and Promote Hair Follicle Conversion from Telogen to Anagen in Mice
This study found that treatment with mesenchymal stem cell extracellular vesicles enhanced hair growth in mice and stimulated dermal papilla cell activity and growth factor production in vitro.
research Hair Follicle Growth by Stromal Vascular Fraction-Enhanced Adipose Transplantation in Baldness
This study found that scalp injection of fat enriched with stem cells may offer a promising alternative for treating early genetic alopecia in both men and women.
research Stem Cells from Human Hair Follicles: First Mechanical Isolation for Immediate Autologous Clinical Use in Androgenetic Alopecia and Hair Loss
This study reported that using human follicle stem cells isolated from hair bulge areas increased hair density by about 29% over baseline in patients with androgenetic alopecia, with significant improvements observed 23 weeks after the last treatment.
research Hair Regeneration Therapy: Application of Adipose-Derived Stem Cells
In this study, Japanese patients treated with adipose-derived stem cell-conditioned medium for hair regeneration showed positive outcomes, suggesting it may be an effective new therapy for alopecia.
research A Critical Assessment of the Evidence for Low-Level Laser Therapy in the Treatment of Hair Loss
This review discusses the current evidence and highlights gaps in research needed for the wider acceptance of low-level laser therapy as a treatment for hair loss; no new clinical results are provided.
research Stem Cell Therapy as a Novel Therapeutic Intervention for Resistant Cases of Alopecia Areata and Androgenetic Alopecia
This study observed that autologous bone marrow derived mononuclear cells and follicular stem cells were both safe and effective for improving resistant alopecia areata and androgenetic alopecia, with no serious adverse events.
research Clinical Use of Conditioned Media of Adipose Tissue-Derived Stem Cells in Female Pattern Hair Loss: A Retrospective Case Series Study
This retrospective study found that adipose-derived stem cell-conditioned media increased hair density and thickness in women with female pattern hair loss over 12 weeks, with no severe adverse effects reported.
research Drug Discovery for Alopecia: Gone Today, Hair Tomorrow
This review discusses current knowledge on the biological mechanisms of different types of alopecia but reports no new clinical findings; the authors highlight future research directions, especially regarding epidermal stem cells and immune pathways.
research A Review of Adipocyte Lineage Cells and Dermal Papilla Cells in Hair Follicle Regeneration
This review discusses recent advances in the role of dermal papilla cells and adipocyte lineage cells in hair regeneration, but it reports no new clinical results.
research Health Status, Coping Strategies, and Alexithymia in Subjects with Androgenetic Alopecia
This study found that people with androgenic alopecia, particularly women, are more prone to anxiety and depression, often adopting avoidant coping strategies, which are linked to emotional and psychological impacts rather than clinical severity.
research Hair Follicle Stem Cell Differentiation Is Inhibited Through Cross-Talk Between Wnt/β-Catenin and Androgen Signaling in Dermal Papilla Cells From Patients With Androgenetic Alopecia
This study found that androgens inhibit hair follicle stem cell differentiation by disrupting the Wnt signalling pathway in dermal papilla cells, but Wnt activation can restore differentiation.
research The Ludwig Pattern of Androgenetic Alopecia Is Due to a Hierarchy of Androgen Sensitivity Within Follicular Units That Leads to Selective Miniaturization and a Reduction in the Number of Terminal Hairs Per Follicular Unit
This study found that women with androgenetic alopecia experience diffuse hair loss due to a decrease in terminal hairs and an increase in vellus hairs per follicular unit.
research Follicular Miniaturization in Female Pattern Hair Loss: Clinicopathological Correlations
This study found that as hair loss severity increased in women with female pattern hair loss, the number of vellus follicles also rose, indicating miniaturization of terminal hair follicles.
research Modulation of the Differentiated Phenotype of Keratinocytes of the Hair Follicle and Epidermis
This review examines the differentiation potential of epithelial cells from various sources in hair follicle formation, concluding that complex interactions are required for hair-specific characteristics, which were achieved in vivo but not in vitro.
Related Research
4 / 4 resultsresearch Platelet-Rich Plasma Effect on Androgenetic Alopecia and Female Pattern Hair Loss
This study found no significant immediate hair growth or loss reduction from PRP treatment compared to Finastride and placebo, but differences emerged after three to six months.
research Protection Against Chemotherapy-Induced Alopecia: Targeting ATP-Binding Cassette Transporters in the Hair Follicle
This article describes a potential novel approach to reduce chemotherapy-induced hair loss by enhancing the expression of specific transporters in hair follicles, but reports no clinical results.
research Pathobiology of Chemotherapy-Induced Hair Loss
This review discusses the pathobiology of chemotherapy-induced alopecia and highlights challenges in managing it, reporting no new clinical results and emphasizing the need for well-designed preclinical models to develop effective treatments.
research Towards a Molecular Understanding of Hair Loss and Its Treatment
This review discusses common hair loss conditions and explores how advancements in hair follicle biology might lead to more effective treatments but reports no new results.