This study suggests that ethyl acetate extract of Equisetum debile may be effective for functional food and nutraceutical use due to its strong 5α-reductase, IL-6 inhibition, and lipid peroxidation activities without cytotoxic effects.
August 2015 in “아시안뷰티화장품학술지” This study found that ultrasonic (ethanol) extracts of Salvia miltiorrhiza bunge and Scutellaria baicalensis were most effective for cell proliferation, while ethanol and ultrasonic waves (water) methods had high antioxidant activity, suggesting their potential in functional cosmetics.
1 citations
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January 2012 in “Ancient Science of Life” This study found that the ethanol extract of Eclipta alba significantly reduced gastric lesions and enhanced gastroprotective activity in ulcer-induced rats, suggesting potent antisecretory effects potentially linked to antioxidant properties.
36 citations
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December 2002 in “Experimental dermatology” This study found that procyanidin B-3, a compound isolated from barley extract, may promote hair growth by enhancing hair epithelial cell growth and counteracting TGF-β1's growth-inhibiting effects in vitro and in vivo.
January 2000 in “Time to knit” This article describes the extraction and characterization method for wedelolactone from Eclipta alba but presents no new clinical results.
December 2014 in “Research and Reviews: Journal of Pharmacology and Toxicological Studies” This study found that applying pet ether extract of Brassica oleracea to rats' skin promoted earlier and longer anagen phases in hair growth, outperforming 1% minoxidil.
1 citations
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July 2025 in “Functional Foods in Health and Disease” This study found that supplementation with CL22209, a standardized Asparagus racemosus root extract, significantly reduced menopausal symptoms and improved hormonal regulation among early perimenopausal women, with notable improvements in vasomotor and menstrual symptoms compared to placebo, while being safe and well-tolerated over 120 days.
January 2020 in “Cosmetics” This study found that Ecklonia cava extract increased skin hydration and decreased redness, suggesting potential benefits for protecting and repairing scalp skin from pollutant-induced damage.
In this study, applying Yeast Constituent Extract twice daily for six months significantly improved hair growth and increased growth factor contents in patients with androgenic alopecia.
1 citations
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January 2025 in “Reproductive Biology and Endocrinology” This study suggests that supplementing with a cell-free fat extract might enhance embryo development and improve clinical outcomes in older women experiencing in vitro fertilization failure.
January 2025 in “Current Issues in Molecular Biology” This study explored the anti-hair loss potential of plant extracts like licorice, salvia miltiorrhiza, and others, finding they increased ALP and β-catenin expression and reduced TGF-β1 and IL-6 in human dermal papilla cells without cytotoxicity.
July 2021 in “Research Square (Research Square)” In this study, the ethyl acetate extract of Semecarpus anacardium Linn leaves was reported to induce cytotoxicity in cancer cells, cause cell cycle arrest, and suppress tumor growth in mice.
3 citations
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May 2021 in “Genetics and Biodiversity Journal” In this study, the ethanolic extract of Citrullus colocynthis demonstrated strong antioxidant activity and reduced cancer cell numbers in vitro, suggesting potential for pharmacological use.
October 2024 in “Asian Pacific Journal of Cancer Prevention” This study found that methanolic extract from Cnicus Benedictus leaves inhibits the growth of human cervical cancer cells in vitro and selectively targets cancer cells over normal cells, suggesting potential safety in its efficacy.
December 2013 in “대한피부미용학회지” In this study, wheat sprout extract (fr. 5) application was associated with increased hair growth in C57BL/6 mice, suggesting its potential as a hair remedy product.
9 citations
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April 2019 in “Molecules” This study found that a blackcurrant extract with phytoestrogen activity increased hair number and stem cell marker expression in a menopausal rat model, suggesting a potential benefit for hair loss.
50 citations
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May 2011 in “Journal of Ethnopharmacology” In this cell study, Eclipta alba extract inhibited cancer cell proliferation and induced apoptosis, showing potential antiproliferative and anti-metastasis effects on liver and related cancer cell lines.
March 2026 in “Jurnal Ilmiah Ibnu Sina (JIIS) Ilmu Farmasi dan Kesehatan” In this in vitro study, the researchers found that garden balsam leaf extract serum showed no antifungal inhibition against Candida albicans, while the positive control, a 2% ketoconazole shampoo, demonstrated a strong effect.
January 2025 in “Open Medicine” This study found that high-concentration cell-free adipose extract effectively reduced collagen deposition and blood vessel formation in a rabbit ear model, showing promise for preventing and treating hypertrophic scars.
13 citations
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May 2019 in “Cancer Prevention Research” This study found that a three-month regimen of leucoselect phytosome, a grape seed extract complex, was well tolerated and significantly reduced bronchial proliferation markers in heavy active and former smokers.
January 2017 in “한국약용작물학회지” This study suggests that 70% ethanol extracts from certain medicinal plants may promote hair growth and be useful for developing hair care products.
January 2023 in “Applied sciences” This study suggests that Equisetum debile extracts, particularly the ethyl acetate fraction, may offer natural cosmeceutical benefits for treating hyperpigmentation, delaying skin aging, and remediating hair loss due to androgenic alopecia.
February 2020 in “Definitions” This article discusses a proprietary botanical lotion with potential to reverse chemotherapy-induced alopecia, restore hair cycles, and improve patient wellbeing; however, it reports no new clinical results.
10 citations
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November 2019 in “Journal of Traditional and Complementary Medicine” This study found that oral treatment with Chamaecyparis obtusa var. formosana leaf extracts improved glucose metabolism and reduced insulin resistance in hyperglycemic rats, suggesting potential as a diabetes health supplement.
January 2026 in “Journal of Applied Pharmaceutical Science” This study identified that the ethanol extract of Selaginella doederleinii may enhance the effectiveness of doxorubicin in treating cervical cancer cells while also providing chemopreventive benefits.
June 2025 in “Universities Journal of Phytochemistry and Ayurvedic Heights” This study evaluated the wedelolactone content and antimicrobial activity of Eclipta alba and Wedelia chinensis extracts, finding a potential relationship between the concentration of wedelolactone and their in vitro antimicrobial effects against several pathogenic bacteria and yeast.
January 2021 in “Natural Products Chemistry & Research” This study found that Datura metel leaf and flower extracts could improve hair growth, with leaf extracts prompting quicker growth and mixed extracts enhancing overall regrowth effectiveness in animal models.
August 2026 in “Pakistan Journal of Pharmaceutical Sciences” In rats with cyclophosphamide-induced hair loss, this study found that applying cetirizine HCl-loaded emulgel with microneedling stimulated hair growth, suggesting a potentially safer alternative to minoxidil for treating chemotherapy-induced alopecia.
8 citations
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August 2019 in “Journal of Drug Delivery and Therapeutics” This study aimed to formulate and evaluate a herbal gel containing Allium cepa extract for its physical properties, such as appearance, viscosity, and spreadability, but it does not report specific results or effectiveness in preventing hair loss.
April 2023 in “Journal of Investigative Dermatology” In this study, a new emulsion containing CBD and ginger root extract significantly reduced symptoms of dry and eczema-prone skin, such as erythema and itching, in a clinical trial.