Screening of Anti-Hair Loss Plant Raw Materials Based on Reverse Network Pharmacology and Experimental Validation
January 2025
in “
Current Issues in Molecular Biology
”
licorice salvia miltiorrhiza mulberry leaf ephedra curcumae radix reverse network pharmacology human dermal papilla cells ALP VEGF TGF-β1 IL-6 Wnt/β-catenin signaling pathway hair follicle growth salvia mulberry turmeric dermal papilla cells alkaline phosphatase vascular endothelial growth factor transforming growth factor beta 1 interleukin 6 Wnt signaling hair growth
Studysummary This study explored the anti-hair loss potential of plant extracts like licorice, salvia miltiorrhiza, and others, finding they increased ALP and β-catenin expression and reduced TGF-β1 and IL-6 in human dermal papilla cells without cytotoxicity.
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