Study on the Cell Proliferation and Antioxidant Activity Effects of Different Extraction Methods of Salvia Miltiorrhiza Bunge and Scutellaria Baicalensis
August 2015
in “
아시안뷰티화장품학술지
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Salvia miltiorrhiza bunge Scutellaria baicalensis hydrothermal extraction distillation organic solvents ethanol extraction ultrasonic waves extraction MTT assay cell proliferation DPPH radical scavenging activity antioxidant status functional cosmetics anti-hair loss products Danshen Baikal skullcap ethanol ultrasonic extraction antioxidants hair loss treatments
TLDR Ethanol and ultrasonic wave extraction methods are best for making effective cosmetics and anti-hair loss products.
This research aimed to identify the most effective extraction method for active ingredients from Salvia miltiorrhiza bunge and Scutellaria baicalensis for potential use in functional cosmetics. The study compared hydrothermal, distillation, organic solvents (ethanol), and ultrasonic waves (ethanol and water) extraction methods. The MTT assay showed that ultrasonic (ethanol) extracts had the highest cell proliferation effect, with 142% for Salvia miltiorrhiza bunge and 134.5% for Scutellaria baicalensis. The DPPH radical scavenging activity test indicated high antioxidant status for all methods, particularly ethanol and ultrasonic waves (water) extracts, with values over 86%. These findings suggested that ethanol and ultrasonic waves (water) extraction methods are most suitable for developing functional cosmetics and anti-hair loss products.