Switching RU vehicle due to scalp irritation – anyone tried low-EtOH + squalane / emu oil?
    Treatment 12/6/2025

    From the encyclopedia
    RU58841 →

    Experimental topical anti-androgen sold as a research chemical

    Dutasteride →

    5-alpha reductase inhibitor that blocks both enzyme types, a stronger DHT blocker than finasteride

    Minoxidil →

    Vasodilator used on the scalp and, at low doses, as a tablet

    At a glance
    In this question or advice post, the primary subjects mentioned are
    💧 RU58841 (topical) 25-50 mg rotating schedule 5-6 years
    💊 Dutasteride (oral) long-term
    💊 Minoxidil (oral)
    the tone is 😐 neutral with maintained pretty well results.

    Other terms

    The user is experiencing scalp irritation from using RU58841 with a 70% ethanol and 30% propylene glycol vehicle and is considering switching to a less irritating vehicle, such as 30% ethanol with 70% squalane or emu oil. They are seeking feedback on the effectiveness and irritation levels of these alternative carriers.
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    5 / 5 results

      community What do you mix your RU58841 powder with?

      in Product  1 upvotes 1 year ago
      RU58841 powder is mixed with a 70% ethanol and 30% propylene glycol solution, with some users seeking PG-free alternatives. Minoxidil is also mentioned as a treatment option.

      community Ru58841 20mg….making my own solution

      in Treatment  1 upvotes 1 year ago
      The conversation is about making a 20mg/ml RU58841 solution for hair loss treatment using ethanol and propylene glycol. The user receives advice on calculating the correct amount of RU58841 powder needed.

      community Making own RU58841 scalp lotion

       4 upvotes 2 months ago
      The conversation is about making and selling RU58841 scalp lotion by mixing the powder with ethanol and propylene glycol. The user is considering selling it as a lotion due to import restrictions in their country.

      community RU58841 Users: How chemically unstable is RU58841 in practice?

      in Technology  2 upvotes 1 year ago
      The conversation discusses using RU58841 mixed with topical minoxidil for hair loss, noting its chemical instability and storage challenges. A user shares their experience using RU58841 with ethanol and propylene glycol, mentioning no significant results yet.

      community RU-58841 appears to not be soluble in common Minoxidil solutions

       7 upvotes 1 year ago
      RU-58841 does not dissolve well in common Minoxidil solutions due to water content, requiring a 70/30 ethanol/propylene glycol mix. Users report using separate solutions for RU-58841 and finasteride/Minoxidil for better results.

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