Cosmeceutical Potentials of Equisetum Debile Roxb. Ex Vaucher Extracts
January 2023
in “
Applied sciences
”
Equisetum debile ethyl acetate fraction dichloromethane fraction 5α-reductase inhibition androgenic alopecia total phenolic content tyrosinase inhibition collagenases inhibition skin fibroblast cells horsetail extract EF DF 5-alpha-reductase inhibition hair loss phenolic content tyrosinase collagenase skin cells
TLDR Equisetum debile extracts may help with skin whitening, anti-wrinkle, and anti-hair loss treatments.
The study on Equisetum debile extracts highlights their potential in cosmeceutical applications, particularly for skin-whitening, anti-wrinkle, and anti-hair loss treatments. The ethyl acetate fraction (EF) exhibited the highest total phenolic content and the strongest inhibition of tyrosinase and collagenases, making it promising for skin care. The dichloromethane fraction (DF) showed the strongest 5α-reductase inhibition, suggesting its potential as a natural alternative to finasteride for treating androgenic alopecia. The extracts maintained their bioactivities over three months and were non-toxic to skin fibroblast cells, indicating their safety and stability for cosmetic use.