Improved Transcutaneous Delivery of Cetirizine Hydrochloride for the Treatment of Post-Chemotherapy Alopecia: Poke and Emulgel Approach

    August 2026 in “ Pakistan Journal of Pharmaceutical Sciences ”
    Sana Hassan
    Studysummary In rats with cyclophosphamide-induced hair loss, this study found that applying cetirizine HCl-loaded emulgel with microneedling stimulated hair growth, suggesting a potentially safer alternative to minoxidil for treating chemotherapy-induced alopecia.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on pjps.pk →
    Discuss this study in the Community →

    Research cited in this study 10

    1. Microneedle Technology Integrated With Diverse Therapeutic Modalities for Hair Regrowth in Alopecia Acta Pharmaceutica Sinica B · 2026
    2. Microneedle-Mediated Therapies in Hair Loss: Applications, Mechanisms, and Future Directions Plastic and Aesthetic Research · 2025
    3. Cancer-Related Alopecia Risk And Treatment Current Treatment Options in Oncology · 2025
    4. Hair Follicle Sulfotransferase Activity and Effectiveness of Oral Minoxidil in Androgenetic Alopecia Journal of Cosmetic Dermatology · 2024
    5. Therapeutic Effects of Topical Cetirizine in the Treatment of Female Pattern Hair Loss: A Randomized Controlled Noninferiority Trial Expert Review of Clinical Pharmacology · 2023
    6. The Efficacy of Topical Prostaglandin Analogs for Hair Loss: A Systematic Review and Meta-Analysis Frontiers in Medicine · 2023
    7. Topical Cetirizine for Treating Androgenetic Alopecia: A Systematic Review Journal of Cosmetic Dermatology · 2022
    8. Microneedling and Its Use in Hair Loss Disorders: A Systematic Review Dermatology and therapy · 2021
    9. Efficacy of Cetirizine 1% Versus Minoxidil 5% Topical Solution in the Treatment of Male Alopecia: A Randomized, Single-Blind Controlled Study Journal of Pharmacy and Pharmaceutical Sciences · 2021
    10. Therapeutic Implications of Topical Cetirizine 1% in Treatment of Male Androgenetic Alopecia: A Case-Controlled Study Journal of Cosmetic Dermatology · 2021