August 2026 in “Pakistan Journal of Pharmaceutical Sciences” In rats with cyclophosphamide-induced hair loss, this study found that applying cetirizine HCl-loaded emulgel with microneedling stimulated hair growth, suggesting a potentially safer alternative to minoxidil for treating chemotherapy-induced alopecia.
9 citations
,
October 2018 in “Journal of Cosmetic and Laser Therapy” This study reviewed eight studies investigating transcutaneous drug delivery via fractional laser and microneedling for alopecia treatment, with six studies showing improved hair regrowth over topical therapy alone, suggesting its potential as a promising treatment strategy, although further research is needed to refine treatment parameters.
6 citations
,
January 2024 in “Scars Burns & Healing” This article reviews 12 clinical applications for transcutaneous laser-assisted drug delivery in skin disorders and concludes that it has potential for broader treatment use.
94 citations
,
September 2014 in “Therapeutic Delivery” This review describes recent advances in using nanoparticles for drug delivery to hair follicles, with potential applications in treating skin diseases such as alopecia and acne, but reports no new findings.
323 citations
,
April 2006 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that 40 nm nanoparticles can effectively penetrate into hair follicles and epidermal Langerhans cells in human skin samples, potentially enabling efficient transcutaneous vaccine delivery.