The Efficacy of Topical Cetirizine Using Microneedling in Androgenetic Alopecia Male Patients

    April 2025 in “ Archives of Dermatological Research ”
    Yasser Mostafa Gohary, Basma Mohamed Mohamed Elkastawy, Hasnaa Osama, Mona Abdellatif
    Studysummary In this study, microneedling-administered topical cetirizine was observed to significantly enhance hair density and increase vellus hair prevalence in men with androgenetic alopecia, with no notable adverse effects reported.
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    Research cited in this study 22

    1. Efficacy of Topical Cetirizine 1% in Treatment of Androgenic Alopecia: Clinical and Dermoscopic Evaluation Research Square (Research Square) · 2023
    2. A Systematic Review of Clinical Trials Using Single or Combination Therapy of Oral or Topical Finasteride for Women in Reproductive Age and Postmenopausal Women with Hormonal and Nonhormonal Androgenetic Alopecia Advances in Clinical and Experimental Medicine · 2023
    3. Topical Cetirizine for Treating Androgenetic Alopecia: A Systematic Review Journal of Cosmetic Dermatology · 2022
    4. Overexpression of miR-122 Promotes Apoptosis of Dermal Papilla Cells by Directly Targeting IGF1R in Androgenetic Alopecia Cell Biology International · 2021
    5. Therapeutic Implications of Topical Cetirizine 1% in Treatment of Male Androgenetic Alopecia: A Case-Controlled Study Journal of Cosmetic Dermatology · 2021
    6. Implications of Cigarette Smoking on Early-Onset Androgenetic Alopecia: A Cross-Sectional Study Journal of Cosmetic Dermatology · 2020
    7. Sunscreen and Facial Skincare Products in Frontal Fibrosing Alopecia: A Case-Control Study British Journal of Dermatology · 2018
    8. Review of Applications of Microneedling in Dermatology Clinical, Cosmetic and Investigational Dermatology · 2017
    9. A Preliminary Study on Topical Cetirizine in the Therapeutic Management of Androgenetic Alopecia Journal of Dermatological Treatment · 2017
    10. Androgenetic Alopecia: An Update Of Treatment Options Drugs · 2016
    11. Female Pattern Hair Loss: A Retrospective Study in a Tertiary Referral Center International Journal of Trichology · 2016
    12. Does Prostaglandin D2 Hold the Cure to Male Pattern Baldness? Experimental Dermatology · 2014
    13. The Contribution of Endogenous and Exogenous Factors to Male Alopecia Plastic and Reconstructive Surgery · 2013
    14. The Contribution of Endogenous and Exogenous Factors to Female Alopecia Plastic and Reconstructive Surgery · 2012
    15. Prostaglandin D2 Inhibits Hair Growth and Is Elevated in Bald Scalp of Men with Androgenetic Alopecia Science Translational Medicine · 2012
    16. Serenoa Repens: Does It Have Any Role in the Management of Androgenetic Alopecia? Journal of Cutaneous and Aesthetic Surgery · 2009
    17. Male Pattern Androgenetic Alopecia in an Indian Context: A Perspective Study Journal of The European Academy of Dermatology and Venereology · 2007
    18. Androgenetic Alopecia in Men Aged 40-69 Years: Prevalence and Risk Factors British Journal of Dermatology · 2003
    19. Is Androgenetic Alopecia a Photoaggravated Dermatosis? Dermatology · 2003
    20. Molecular Mechanisms of Androgenetic Alopecia Experimental Gerontology · 2002
    21. The Prevalence and Types of Androgenetic Alopecia in Korean Men and Women British Journal of Dermatology · 2001
    22. Comparison of Finasteride (Proscar) and Serenoa Repens (Permixon) in the Inhibition of 5-Alpha Reductase in Healthy Male Volunteers European Urology · 1994

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    2. Efficacy of Topical Cetirizine 1% in Treatment of Androgenic Alopecia: Clinical and Dermoscopic Evaluation Research Square (Research Square) · 2023
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