46 citations
,
September 2014 in “Tissue engineering. Part A” Researchers created hair-inducing human cell clusters using a 3D culture method.
27 citations
,
March 2014 in “Experimental Dermatology” IGF-1 affects hair loss and could be a potential treatment.
11 citations
,
April 2013 in “Journal of Proteomics” Found different proteins in balding and non-balding cells, giving insight into hair loss causes.
115 citations
,
September 2012 in “Experimental Dermatology” Androgens have complex effects on hair growth, promoting it in some areas but causing hair loss in others, and our understanding of this is still evolving.
72 citations
,
January 2012 in “Annals of Dermatology” The study found that insulin-like growth factor-I (IGF-I) promoted hair growth by extending the anagen phase and increasing hair growth rate in an organ culture model of 140 hair follicles from 3 individuals. IGF-I enhanced hair growth to 0.10 mm/day compared to 0.08 mm/day in the control group and maintained 70.8% of hair follicles in the anagen phase by day 12, versus 45.8% in controls. This effect was linked to IGF-I's anti-apoptotic properties and the upregulation of platelet-derived growth factors PDGF-A and PDGF-B, preventing hair follicles from entering the catagen phase.
10 citations
,
July 2011 in “British Journal of Dermatology” Lower growth factors linked to balding in androgenetic alopecia.
149 citations
,
June 2010 in “The FASEB journal” miR-31 regulates hair growth by controlling gene expression in hair follicles.
19 citations
,
January 2009 in “Journal of The European Academy of Dermatology and Venereology” Bald areas have lower cell growth, more DNA damage, and increased cell death.
