12 citations,
May 2015 in “Molecular Medicine Reports” Troxerutin helps protect skin cells from oxidative stress and may be good for treating hair loss.
12 citations,
January 2015 in “Indian Journal of Dermatology, Venereology and Leprology” Negative expectations can cause adverse effects in dermatology treatments, like with finasteride for baldness, and careful communication can help reduce these nocebo responses.
11 citations,
September 2021 in “Journal of molecular endocrinology” ERβ has potential in treating prostate cancer and neurodegenerative diseases, but human studies are needed before clinical use.
11 citations,
September 2013 in “Journal of the Egyptian Women's Dermatologic Society (Print)” Various treatments exist for hair loss, but more research is needed for better options.
10 citations,
May 2020 in “Dermatology Research and Practice” Proteoglycans are important for hair growth, and a specific treatment can help reduce hair loss.
10 citations,
May 2018 in “Neuropharmacology” Drugs for hormone-related conditions might help treat mental disorders but could have serious side effects.
10 citations,
May 2018 in “Cell death discovery” HSP90 and lamin A/C are crucial for hair growth and could be targets for treating hair loss.
9 citations,
February 2022 in “Nature communications” Rare changes in the KRT82 gene are linked to a higher risk of Alopecia Areata.
8 citations,
March 2020 in “Frontiers in Cell and Developmental Biology” Researchers created immortal human skin cells with constant testosterone receptor activity to study hair loss and test treatments.
8 citations,
June 2019 in “Scientific Reports” Increased PPARGC1α relates to hair thinning in common baldness.
8 citations,
July 2014 in “General and Comparative Endocrinology” Finasteride affects frog testes by increasing testosterone, decreasing 5α-DHT, and impacting genes related to reproduction and other functions.
8 citations,
February 2009 in “Current Women's Health Reviews” Testosterone treatment can improve sexual function and bone density in women but may have adverse effects and requires more research on safety and guidelines.
7 citations,
January 2015 in “Current problems in dermatology” Hair loss can be caused by stress, infections, drugs, and various diseases, with treatment depending on accurate diagnosis.
6 citations,
January 2010 in “Springer eBooks” SA linked to mitochondrial issues and oxidative stress, while AGA involves disrupted hair growth genes.
4 citations,
October 2022 in “Frontiers in public health” Cadmium chloride pollution can cause skin disorders, speed up aging, and prevent hair growth.
3 citations,
July 2023 in “Biomolecules” B2m-free HLA variants may be a new class of HLA important in immune responses and diseases.
1 citations,
November 2023 in “iScience” A protein called desmoglein 3 is important for keeping hair follicle stem cells inactive and helps in their regeneration.
1 citations,
January 2015 in “Journal of nutrition & health” Fish oil improves skin health in people with diabetes and high cholesterol.
May 2024 in “Journal of Education, Health and Sport” Current treatments for folliculitis decalvans include antibiotics, isotretinoin, and potential new therapies like botulinum toxin A and PRP.
March 2024 in “International Journal of Cosmetic Science” Dandruff is linked to increased T cells and weakened immune protection in hair follicles.
November 2023 in “Frontiers in Neuroendocrinology” Some people experience lasting sexual, psychological, and sleep problems after using finasteride or SSRI antidepressants, possibly due to similar underlying causes.
March 2021 in “Research Square (Research Square)” Patients with RASopathies have a higher risk of autoimmune disorders and should be routinely screened.
77 citations,
May 2012 in “Expert Opinion on Emerging Drugs” New treatments for male hypogonadism are effective and should be personalized.
April 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” GRK2 is essential for healthy hair follicle function, and its absence can lead to hair loss and cysts.
8 citations,
July 2022 in “BMC neuroscience” Transplanted hair follicle stem cells improved brain function and reduced damage after a stroke in rats.
1 citations,
January 2024 in “Theranostics” Exosomes show promise for future tissue regeneration.
408 citations,
January 2017 in “Science” Some wound-healing cells can turn into fat cells around new hair growth in mice.
45 citations,
April 2016 in “Journal of Dermatological Science” The Wnt/β-catenin pathway can activate melanocyte stem cells and may help regenerate hair follicles.
43 citations,
February 2019 in “International immunology” Special immune cells called Regulatory T cells help control skin inflammation and repair in various skin diseases.
24 citations,
July 2011 in “PubMed” Thyroid hormones affect skin texture, hair and nail growth, and can cause skin diseases related to thyroid problems.