Stem Cells In Regenerative Medicine: A Journey From Adult Stem Cells To Induced Pluripotent Cells

    Ylenia Della Rocca, A. Mazzone, Guya Diletta Marconi, Oriana Trubiani, Jacopo Pizzicannella, Francesca Diomede
    TLDR Induced pluripotent stem cells are a major breakthrough in regenerative medicine.
    The review explores the potential of stem cells in regenerative medicine, focusing on adult stem cells and induced pluripotent stem cells (iPSCs) for treating various diseases, including liver, neurological, musculoskeletal, lung, and cardiovascular conditions. It highlights promising results in dermatological disorders like androgenetic alopecia and alopecia areata through stem cell therapy. Despite the potential, few clinical trials have resulted in approved therapies, indicating a need for further research. The document also discusses the roles of neural and skin stem cells, mesoderm-derived stem cells, and mesenchymal stem cells (MSCs) in regenerative applications, noting both their therapeutic potential and challenges such as immune response and oncogenic risks.
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