Solubilizing Steroidal Drugs by Beta-Cyclodextrin Derivatives

    Dennis H. Schwarz, Annegret Engelke, Gerhard Wenz
    Studysummary This study found that anionic HSES achieved high complexation efficiencies with various steroids, significantly enhancing their solubility, while specific β-cyclodextrin thioethers showed selective binding to testosterone and estradiol.
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    Research cited in this study 4

    1. Long-Term Use of 5α-Reductase Inhibitors and the Risk of Male Breast Cancer Cancer Causes & Control · 2014
    2. Persistent Sexual Side Effects of Finasteride for Male Pattern Hair Loss The Journal of Sexual Medicine · 2011
    3. Binary and Ternary Inclusion Complexes of Finasteride in HPβCD and Polymers: Preparation and Characterization Bioorganic & Medicinal Chemistry · 2009
    4. Enhancement of Follicular Delivery of Finasteride by Liposomes and Niosomes International Journal of Pharmaceutics · 2006